Programs

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Mechanisms of development, injury and repair in the vertebrate auditory system

Key words
hearing, vestibular, sensory, development, regeneration, macrophage, microglia

Program affiliation
General

Research summary
Identification of tumor specific mutant antigens recognized by the immune system as foreign that serve as the target of a T-cell response against tumors

Key words

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics

Research summary
Understand how people think about health risks and how those thoughts influence their health-related decisions and behavior

Key words

Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Human and Statistical Genetics

Research summary
Detection and molecular classification of rare tumor cells to predict and mitigate cancer metastases

Key words
cancer, functional genomics, gene expression, pathogenesis, breast cancer

Program affiliation
Cancer Biology
Immunology

Research summary
We are focused on exploiting features of the tumor microenvironment for cancer therapy. Specifically, we study stromal - tumor cell interactions in pancreatic cancer with the goal of defining clinically relevant cancer biology.

Key words
pancreatic cancer, immunotherapy, myeloid cells, tumor microenvironment, CRISPR screening

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Tumor suppressor and oncogene networks in cancer biology

Key words
Breast cancer, lung cancer, tumor suppressors, oncogenes, microfluidics, RNA editing, metastasis

Program affiliation
Neurosciences
Molecular Cell Biology

Research summary
The interplay between the ubiquitin-proteasome and autophagy pathways in skeletal muscle and neurodegenerative disorders

Key words
protein production and clearance, proteasome, skeletal muscle, inclusion body, autophagy

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Molecular mechanisms through which tumor cells metastasize to bone

Key words
cancer, bone biology, integrin biology, metastasis

Program affiliation
Biochemistry Biophysics and Structural Biology
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis

Research summary
Antibiotic drug discovery

Key words
Organic Chemistry, Biological Chemistry, Organic Synthesis, Natural Products, Antibiotics, Biosynthesis, Enzymes, Enzyme Inhibitors, Drug Delivery, Anticancer Agents, Diversity-Oriented Synthesis

Program affiliation
Neurosciences
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
Elucidating human brain connectivity during different states of arousal, across the lifespan, and in health and disease.

Key words
EEG, fMRI, infants, babies, development, aging, Alzheimer's disease, degeneration, sleep