Programs

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Computational and Systems Biology
Molecular Genetics and Genomics

Research summary
Host-microbe dynamics during pregnancy

Key words
virome, microbiome, pregnancy, papillomavirus, herpesvirus

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Cancer Biology

Research summary
The Xiao Lab builds AI and computational methods for digital pathology and multimodal data integration to advance precision oncology. We develop interpretable deep learning and spatial statistical models that link tissue morphology with molecular and clinical data to predict patient outcomes and guide therapy. Our work is highly collaborative, bridging pathology, oncology, radiology, and data science, with a strong emphasis on external validation and clinical translation.

Key words
Computational pathology; Artificial intelligence; Deep learning; Spatial-omics; Multimodal data integration; Precision oncology

Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology
Cancer Biology

Research summary
Alzheimer’s disease, Parkinson's disease, central nervous disorders, postmortem biomarker validation and characterization, in vivo positron emission tomography, in vitro quantitative autoradiography

Key words
Imaging, biomarkers, cancer, neuroscience, PET, quantitative autoradiography, pharmaceuticals, biological assays, human brain function and disease

Program affiliation
Neurosciences

Research summary
Development and applications of quantitative MRI-based methods and Machine Learning tools for in vivo studying of humans and animals in health and disease

Key words
brain structure and function, Alzheimer`s disease, Multiple Sclerosis, MRI, fMRI, GEPCI, hyperpolarized gas, biophysics, mathematical modeling, Machine Learning

Program affiliation
General

Research summary
Understanding the role of the cerebellar nodulus and uvula (NU) in motion perception and spatial navigation

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
We develop various light-wave based technologies, such as novel sensors, spectroscopy and imaging systems, for biological and medical applications.

Key words
nanotechnology, photonics, material physics, biosensing, spectroscopy, imaging

Program affiliation
Biomedical Informatics and Data Science
Human and Statistical Genetics

Research summary
My research is focused on investigating the genetic determinants of under-studied musculoskeletal phenotypes, determining the impact of occupational burdens on musculoskeletal disease, and understanding interactions between genetic and non-genetic risk factors for musculoskeletal disease.

Key words
Genetics, Musculoskeletal Disease, Circadian Rhythm, Occupation, Data Science

Program affiliation
Neurosciences
Molecular Cell Biology

Research summary
Molecular pathogenesis of neurodegenerative diseases

Key words
Huntington's disease, neurodegeneration, molecular mechanisms, epigenetic regulation, gene expression, primary neuron culture, animal models of disease

Program affiliation
Biomedical Informatics and Data Science

Research summary
Focused on applied clinical informatics research to support clinicians adapting to health information technology

Key words

Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding the mechanisms of nervous system construction and dysfunction.

Key words