Plant and Microbial Biosciences
Alex Holehouse, PhD
Associate Professor
- Email: alex.holehouse@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Cell Biology
Plant and Microbial Biosciences
Research summary
Understand how function is encoded into disordered sequences using a combination of computational and experimental approaches
Key words
Disordered proteins, IDPs, IDRs, phase transitions, emergence, deep learning, AI, bird-themed software packages
Scott Hultgren, PhD
Helen L. Stoever Professor
- Email: hultgren@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Interdisciplinary approach combining genetics, genomics, biochemistry, structural biology, high-resolution imaging, animal models, clinical studies and combinatorial chemistry to determine key aspects of bacterial pathogenesis and apply our knowledge to development of new therapeutics.
Key words
antibiotic-sparing therapeutics, host-pathogen interactions, bacterial pathogenesis, drug and vaccine development, multi-drug resistant E. coli, MRSA, Enterococcus, Acinetobacter, Klebsiella, urinary tract infections (UTI)
Joseph Jez, PhD
Spencer T Olin Professor and HHMI Professor
- Email: jjez@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Research summary
Exploring regulatory networks in metabolism - structural biology and biochemistry of plants and microbes
Key words
biochemistry, enzymology, plant biology, protein engineering, protein structure, structural biology
Barbara Kunkel, PhD
Professor
- Email: kunkel@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Research summary
Molecular genetic analysis of disease development in Pseudomonas syringae-Arabidopsis interactions
Key words
plant-microbe interactions, bacterial pathogenesis, auxin, IAA, Type III effector protein, genetics, plant biology
Michele LeRoux, PhD
Assistant Professor
- Email: mleroux@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
We study how bacterial defend themselves from their viral predators, bacteriophage.
Key words
bacteria, phage, bacteriophage, virus
Petra Levin, PhD
George William and Irene Koechig Freiberg Professor
- Email: plevin@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Bacterial growth and antibiotic susceptibility
Key words
Bacterial, growth size, antibiotics, tolerance, antibiotic resistance, systems biology, cytoskeleton, biochemistry, microbiology, microscopy
Fangqiong Ling, PhD
Associate Professor
- Email: fangqiong@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Research summary
A computational and experimental lab studying bacterial colonization and transmission at the boundary of built and natural environments and exploring microbiomes as environmental sensors and public health sentinels
Key words
Lucia Lohmann
George Engelmann Professor of Botany
Program affiliation
Plant and Microbial Biosciences
Research summary
Key words