Yao-Peng Xue

Program: Biochemistry Biophysics and Structural Biology

Current advisor: Gautam Dantas, PhD

Undergraduate university: National Tsing Hua University, 2016

Enrollment year: 2020

Research summary
Evolution of antibiotic resistant proteins

Graduate publications
Blake KS, Xue YP, Gillespie VJ, Fishbein SRS, Tolia NH, Wencewicz TA, Dantas G. 2025 The tetracycline resistome is shaped by selection for specific resistance mechanisms by each antibiotic generation. Nat Commun, 16(1):1452. PMCID: PMC11806011

Li R, Xue YP, Le ST, Tang WK, Tolia NH, Dantas G, Wencewicz TA. 2025 Covalent Irreversible Inhibitors of Tetracycline Destructases. ACS Infect Dis, 11(9):2476-90. PMCID: PMC12467390

Blake KS, Kumar H, Loganathan A, Williford EE, Diorio-Toth L, Xue YP, Tang WK, Campbell TP, Chong DD, Angtuaco S, Wencewicz TA, Tolia NH, Dantas G. 2024 Sequence-structure-function characterization of the emerging tetracycline destructase family of antibiotic resistance enzymes. Commun Biol, 7(1):336. PMCID: PMC10944477