People

Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology

Research summary
Causes and new approaches to curing high-risk pediatric leukemia

Key words
Cancer biology, stem cell, hematopoiesis, leukemia, developmental biology

Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
My laboratory studies the pathogenic role of epigenetic regulators in prostate cancer development and progression, with a focus on the mechanisms by which these factors co-operate with transcription factors to drive tumor heterogeneity and resistance to various standard of care therapies

Key words
Epigenetics, prostate cancer, transcriptomics, small molecule therapeutics, radioresistance, DNA damage signaling, tumor-immune dynamics.

Program affiliation
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Cancer Biology

Research summary
How tyrosine phosphorylation regulates epigenetic processes that affect cellular homeostasis and cancer cell survival

Key words

Program: Neurosciences

Graduation Year: 2021

Thesis Advisor: David M. Holtzman

Thesis Title: Cell-type specific expression of apolipoprotein E by astrocytes and microglia: Implications for the development of amyloid-β pathology in Alzheimer disease.

Program: Developmental Regenerative and Stem Cell Biology

Graduation Year: 2019

Thesis Advisor: Valeria Cavalli

Thesis Title: Transcriptional and Epigenetic Regulation of Axon Regeneration

Program affiliation
Cancer Biology
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics

Research summary
Translational Cancer Genomics; Noncoding RNAs

Key words
non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, solid tumor malignancies

Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
The microtubule cytoskeleton in health and disease

Key words
Cell cytoskeleton, microtubules, cilia, centrosome, cell cycle, signal transduction, kidney/lung development and disease

Program: Molecular Microbiology and Microbial Pathogenesis

Graduation Year: 2023

Thesis Advisor: Gautam Dantas

Thesis Title: Understanding and combating the spread of antibiotic-resistant organisms

Program: Molecular Cell Biology

Graduation Year: 2008

Thesis Advisor: Michael L. Nonet

Thesis Title: The Regulation of Neuronal Function by Exocytic Genes in Caenorhabditis elegans.

Program: Molecular Genetics and Genomics

Graduation Year: 2007

Thesis Advisor: Jeffrey H. Miner

Thesis Title: Discs-Large Homolog 1 (DLGH1) and Laminins in Mouse Tissue Morphogenesis and Maintenance