People

Program: Genetics

Graduation Year: 1997

Thesis Advisor: Timothy J. Ley

Thesis Title: Functional Analysis of Neutrophil and Natural Killer Cell Granzymes in Humans and Mice

Program: Immunology

Graduation Year: 2019

Thesis Advisor: Brian S. Kim

Thesis Title: The Role of Natural Killer Cells in Atopic Dermatitis

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology

Research summary
Investigation of peripheral nerve injury and regeneration

Key words
nerve regeneration, neuropathy, neurotrophins, peripheral nervous system, nerve allotransplantation, tissue engineering

Program: Biomedical Informatics and Data Science

Current advisor: Alex Ramsey, PhD

Undergraduate university: Clemson University, 2019

Program: Human and Statistical Genetics

Graduation Year: 2023

Thesis Advisor: Ting Wang

Thesis Title: Epigenetic perturbation as a means to induce cancer-specific antigens in GBM

Program: Molecular Microbiology and Microbial Pathogenesis

Graduation Year: 2010

Thesis Advisor: Michael G. Caparon

Thesis Title: Characterization of Streptolysin O as the Translocator for the Cytolysin-Mediated Translocation Process in Streptococcus pyogenes

Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology

Research summary
Causes and new approaches to curing high-risk pediatric leukemia

Key words
Cancer biology, stem cell, hematopoiesis, leukemia, developmental biology

Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
My laboratory studies the pathogenic role of epigenetic regulators in prostate cancer development and progression, with a focus on the mechanisms by which these factors co-operate with transcription factors to drive tumor heterogeneity and resistance to various standard of care therapies

Key words
Epigenetics, prostate cancer, transcriptomics, small molecule therapeutics, radioresistance, DNA damage signaling, tumor-immune dynamics.

Program affiliation
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Cancer Biology

Research summary
How tyrosine phosphorylation regulates epigenetic processes that affect cellular homeostasis and cancer cell survival

Key words

Program: Neurosciences

Graduation Year: 2021

Thesis Advisor: David M. Holtzman

Thesis Title: Cell-type specific expression of apolipoprotein E by astrocytes and microglia: Implications for the development of amyloid-β pathology in Alzheimer disease.