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Jarod Roland, MD

Assistant Professor

Program affiliation
Neurosciences

Research summary
My research aims to understand of how brain networks develop and adapt to changes caused by epilepsy, tumors, stroke, and or other neurological injuries. In particular I am interested in how children's brains reorganize after neurosurgical treatment of these conditions.

Key words
intracranial electroencephalography, ieeg, resting state functional MRI, rs-fMRI, brain networks, development, epilepsy, neurosurgery

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David Rosen, MD, PhD

Associate Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Pathogenesis and host response to Klebsiella pneumoniae infections

Key words
Klebsiella pneumoniae, Antibiotic Resistance, Pneumonia, Urinary Tract Infection, Virulence Factors, Adaptive Immunity

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Ronald Rubenstein, MD, PhD

Robert C. Strunk Endowed Chair for Lung and Respiratory Research Professor

Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding the mechanisms by which a novel chaperone of the Endoplasmic Reticulum, ERp29, regulates the biogenesis of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR), the Epithelial Sodium Channel (ENaC), and other proteins related to pediatric pulmonary diseases

Key words
Cystic Fibrosis, Chaperone, Endoplasmic Reticulum, CFTR, ENaC/Epithelial Sodium Channel, Epithelia, Insulin, Trafficking, Biogenesis

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Deborah Rubin, MD

Professor

Program affiliation
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Intestinal stem cells and the stem cell niche in intestinal injury/short bowel syndrome and colitis associated colon cancer, early colon cancer pathogenesis

Key words
Stem cells, epithelial proliferation, cancer, short bowel syndrome

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Joshua Rubin, MD, PhD

Professor

Program affiliation
Cancer Biology
Molecular Cell Biology
Neurosciences

Research summary
Molecular mechanisms in pediatric brain tumorigenesis

Key words
tumor biology, signal transduction, stem cells, neural development, sexual dimorphism, circadaian rhythm, chemokines, cAMP

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David Rudnick, MD, PhD

Associate Professor

Program affiliation
Developmental Regenerative and Stem Cell Biology

Research summary
Molecular mechanisms of liver injury and regeneration

Key words
liver; regeneration; alpha 1 antitrypsin deficiency; liver disease; aflatoxin; acute liver failure; cell cycle; mouse models; epigenetics; metabolism

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Jai Rudra, PhD

Associate Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis

Research summary
Development of nano-scale biomaterials for engaging the immune system to induce protective antibody and cell-mediated immune responses against diseases

Key words

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Yoram Rudy, PhD, FAHA, FHRS

The Fred Saigh Distinguished Professor of Engineering

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
Multiscale studies of cardiac electrophysiology and arrhythmia using computational biology and imaging

Key words
ion channels, protein dynamics, cardiac cell electrophysiology, cardiac imaging

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John Russell, PhD

Professor

Program affiliation
General

Research summary
CNS/lymphocyte interactions regulating inflammation and pathogenesis in a mouse model of multiple sclerosis

Key words
apoptosis, autoimmunity, imaging, inflammation, multiple sclerosis

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Mark Rutherford, PhD

Associate Professor

Program affiliation
Neurosciences

Research summary
Cellular mechanisms underlying our systems of sound and balance encoding in development, in maturity, and in pathology of hearing or vestibular function

Key words
cochlea, neurodegeneration, synapse, excitotoxicity, encoding sound