Faculty

Program affiliation
Neurosciences

Research summary
Information processing in the cerebral cortex

Key words
behavior, cognition, computational biology, eye-hand coordination, neurophysiology, systems neuroscience

Program affiliation
Developmental Regenerative and Stem Cell Biology

Research summary
Inductive and morphogenetic processes that establish and shape germ layers during vertebrate embryogenesis, using zebrafish and embryonic stem cell models

Key words
Gastrulation, Vertebrate embryogenesis, Patterning, Cell movement, Cell signaling, Morphogenesis, Stem Cells

Program affiliation
Neurosciences

Research summary
Imaging CNS function and pathology

Key words
diffusion, imaging, multiple sclerosis, retinal degeneration, spinal cord, White matter injury

Program affiliation
Biochemistry Biophysics and Structural Biology

Research summary
Role of disordered proteins in function and dysfunction: from Alzheimer's disease to SARS CoV 2

Key words
disordered proteins, single molecule, fluorescence, FRET, Alzheimer's disease, SARS CoV 2 nucleocapsid, Apolipoprotein E, ApoE, biomolecular condensates, polymer models

Program affiliation
Biomedical Informatics and Data Science
Neurosciences

Research summary
Intersection of medical image processing, machine learning, data science, and computational neuroscience

Key words

Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Understand how epigenetic mechanisms and chromatin dynamics contribute towards the development of cancer.

Key words
Epigenetics, chromatin, cancer, mouse models, lymphoma, melanoma, EZH2, PRC2, H3K27me3

Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology

Research summary
My research program studies DNA methylation in cancer, with a specific emphasis on understanding the origin, evolution, and functional impact of cancer-associated DNA methylation changes and how these can be used as biomarkers of clinical outcomes.

Key words
epigenetics, methylation, gene regulation, cancer, leukemia, genomics

Program affiliation
General

Research summary
Exosomes- biogenesis and secretion. Hominoid-specific genes such as TBC1D3, that regulate growth factor receptor signaling, may help explain human evolution and physiology

Key words
Exosomes, endocytosis, hominoid-specific genes

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology

Research summary
Molecular pathogenesis of Mycobacterium tuberculosis

Key words
bacteria, gene regulation, molecular genetics, microbiology, pathogenesis, transcription, infectious disease, innate immunity

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Investigate the genetic and environmental factors that underlie the mechanistic basis for the heterogeneity in outcomes in response to infection

Key words