Biochemistry Biophysics and Structural Biology
Nada Abumrad, PhD
Robert C. Atkins Professor of Obesity Research in Medicine
- Email: nabumrad@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Fatty acids regulate energy balance and tissue renewal. Dysfunction of this regulation causes disease
Key words
fatty acid, transport, disease risk
Hema Adhikari, PhD
Assistant Professor
- Email: hema.adhikari@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Cancer Biology
Computational and Systems Biology
Molecular Cell Biology
Research summary
The Adhikari Lab focuses on interrogating RAS oncoprotein signaling networks through the lens of interactomes in cancer, based on an innovative functional proteomics platform combining proximity labeling technology coupled to CRISPR/Cas9 screening.
Key words
biochemistry, cell signaling, proteomics, genomics, cancer, tumorigenesis
Ream Al-Hasani, PhD
Associate Professor
- Email: al-hasanir@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding the endogenous opioid systems to defeat addiction, ameliorate affective disorders, and relieve chronic pain.
Key words
Jennifer Alexander-Brett, MD, PhD
Associate Professor
- Email: jalexand@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Respiratory immunobiology, with particular interest in cytokine pathways associated with lung epithelial progenitors
Key words
Gaya Amarasinghe, PhD
Alumni Endowed Professor
- Email: gamarasinghe@wustl.edu
Program affiliation
Immunology
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Molecular mechanisms at the host-pathogen interface
Key words
biochemistry, structural biology, signaling, virology, host pathogen interactions, immunology
Sadaf Amin, PhD
Assistant Professor
- Email: amins@wustl.edu
Program affiliation
Neurosciences
Developmental, Regenerative and Stem Cell Biology
Molecular Cell Biology
Immunology
Biochemistry, Biophysics, and Structural Biology
Research summary
Our research investigates the role of the innate immune system in the pathogenesis of neurodegenerative diseases and the processes of brain aging, employing stem cell-based platforms and transgenic mouse models to study mechanisms of neuroimmune interactions in the brain.
Key words
Neurodegeneration, Innate Immunity, Aging
Maxim Artyomov, PhD
Associate Professor
- Email: martyomov@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Systems immunology using high-throughput next-generation sequencing in conjunction with mathematical and statistical modeling approaches rooted in statistical physics
Key words
systems immunology, systems biology, computational biology, RNA-seq
Monika Bambouskova, PhD
Assistant Professor
- Email: monika.bambouskova@wustl.edu
Program affiliation
Immunology
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Immunometabolism - metabolic regulation of immune cell activation
Key words
Thomas Baranski, MD, PhD
Professor
- Email: baranski@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Research summary
Signal transduction by G proteins and pathogenesis of diabetes
Key words
diabetes, Drosophila, G protein, hormones, protein structure, signal transduction
Wayne Barnes, PhD
Associate Professor
- Email: barneswm@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Research summary
Possible cure for MS: intravenous access by myelin-binding aptamer; PCR at one temp; RT-enabled Taq pol.
Key words
DNA, aptamers, technology development, brain therapy