Biochemistry Biophysics and Structural Biology
Matthew Lew, PhD
Associate Professor
- Email: mdlew@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Developing novel optical imaging technologies for studying biomolecular activities at the nanoscale
Key words
super-resolution microscopy, single-molecule spectroscopy, optimal imaging system design, nanoscale sensing
Jr-Shin Li, PhD
Associate Professor
- Email: jsli@wustl.edu
Program affiliation
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
Control and optimization of large-scale complex systems with applications ranging from quantum mechanics and neuroscience to bioinformatics
Key words
computational mathematics, control theory, optimization, dynamical systems, MRI, NMR, neuroscience
Weikai Li, PhD
Roy and Diana Vagelos Professor of Biochemistry and Molecular Biophysics
- Email: weikai@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Membrane protein structure and function
Key words
structure biology, enzymology, membrane proteins, molecular medicine, mass spectrometry, cardiovascular biology, immunology, hematology
Xiaowei Li, PHD
Assistant Professor
- Email: xiaoweili@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Neurosciences
Research summary
The Li laboratory is dedicated to developing biomaterial platforms for regenerative medicine, specifically focusing on applications in angiogenesis, vascularization, stem cell engineering, and tissue regeneration.
Key words
Biomaterials, Tissue Engineering, Regenerative Medicine
Christopher Lingle, PhD
Professor
- Email: clingle@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Research summary
Structure-function studies of Slo family K+ channels
Key words
ion channel, protein structure, neurobiology, physiology, cell signaling
Timothy Lohman, PhD
Marvin A. Brennecke Professor of Biophysics
- Email: lohman@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Mechanisms of DNA helicases/translocases and SSB proteins
Key words
DNA recombination, DNA replication, fluorescence, molecular motors, single molecules, thermodynamics
Nupam Mahajan, PhD
Professor
- Email: nupam@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Cancer Biology
Research summary
How tyrosine phosphorylation regulates epigenetic processes that affect cellular homeostasis and cancer cell survival
Key words
Moe Mahjoub, PhD
Associate Professor
- Email: mmahjoub@wustl.edu
Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
The microtubule cytoskeleton in health and disease
Key words
Cell cytoskeleton, microtubules, cilia, centrosome, cell cycle, signal transduction, kidney/lung development and disease
Michael Major, PhD
Alan A. and Edith L. Wolff Professor
- Email: bmajor@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Research summary
Studying how perturbation of specific signal transduction pathways contributes to the initiation, progression and dissemination of cancer
Key words
proteomics, functional genomics, lung cancer, signal transduction, WNT, oxidative stress
Susruta Majumdar, PhD
Professor (PEFA)
- Email: susrutam@wustl.edu
Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology
Research summary
Research in the laboratory is aimed at attaining functional selectivity of opioid agonist action from its own target adverse effects while integrating chemical synthesis with biochemical, genetic and pharmacological approaches.
Key words
opioids, GPCRs, biased signaling, pain, chemical biology
