Biochemistry Biophysics and Structural Biology
Robert Mercer, PhD
Professor
- Email: rmercer@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Molecular and cell biology of ion pumps and transporters in plasma membrane; cell polarity
Key words
cell membrane, development, Na K-ATPase, excitable tissue, cell volume
Timothy Miller, MD, PhD
Professor
- Email: miller.t@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Mechanisms of neurodegeneration and targeted therapies for neurodegenerative diseases
Key words
ALS (amyotrophic lateral sclerosis), SOD1, TDP-43, C9ORF72, miRNA, Tau, Dementia, Neurodegeneration, Antisense oligonucleotides
Liviu Mirica, PhD
Assistant Professor
- Email: mirica@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Development of specific inhibitors of histone demethylases; design of therapeutic and imaging chemical agents for Alzheimer's disease
Key words
Alzheimer’s disease, bioinorganic chemistry, drug design, enzymology, histone modification, redox processes
Makedonka Mitreva, PhD
Professor
- Email: mmitreva@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Research summary
Next-generation experimental, multi-omic and computational approaches to empower the study of infectious diseases and the human microbiome
Key words
Genomics of Infectious Diseases, Helminth Genomics, Human Metagenomics
Kevin Moeller, PhD
Professor
- Email: moeller@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Developing new methods for peptide mimetic, natural product synthesis, and the construction of addressable molecular arrays
Key words
biosensors, electrochemistry, medicinal chemistry, organic synthesis, reactive intermediates
Jose Moron-Concepcion, PhD
Professor
- Email: jmoron-concepcion@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Elucidating the molecular mechanisms underlying opiate dependence
Key words
opioids, addiction, pain, molecular mechanisms, animal models
Nima Mosammaparast, MD, PhD
Associate Professor
- Email: nima@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding how RNA modifications influence transcription, signaling, and genomic integrity
Key words
RNA modifications, cancer , transcription, DNA repair
Shankar Mukherji, PhD
Assistant Professor
- Email: smukherji@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Systems and synthetic cell biology: quantitative analysis of cellular organization
Key words
Colin Nichols, PhD
Carl Cori Professor
- Email: cnichols@wustl.edu
Program affiliation
Molecular Cell Biology
Neurosciences
Biochemistry Biophysics and Structural Biology
Research summary
Ion channel biology in health and disease
Key words
ion channel, neurobiology, functional genomics, cell signaling, kinetics
Natalie Niemi, PhD
Assistant Professor
- Email: niemi@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Understanding how mitochondria are built, regulated, and maintained
Key words
mitochondria, phosphorylation, metabolism, signaling, kinase, phosphatase