Biochemistry Biophysics and Structural Biology

Program affiliation
Computational and Systems Biology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Metabolism analysis and metabolic engineering of environmental microorganisms for biofuel/chemical production

Key words
Metabolic flux analysis, bioenergy, metabolic engineering, algal bioprocess, bioremediation, kinetic modeling

Program affiliation
Neurosciences
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
Applying concepts and methods from statistical physics and mathematics to the study of the brain

Key words
theoretical and computational neuroscience, statistical physics

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology

Research summary
Structure-activity relationships in UV mutagenesis; nucleic acid-based chemotherapeutic and imaging agents

Key words
cancer, drug delivery, imaging, mutagenesis, nanotechnology, telomere

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology

Research summary
Epigenetic regulation of phenotypes by propagation of prions in yeast

Key words
amyloid, chaperones, epigenetics, neurodegeneration, prion, yeast

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology

Research summary
Biophysical mechanisms of infectious disease

Key words

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
Understanding DNA repair mechanisms that impact cancer etiology and responses to chemotherapies

Key words
DNA repair and replication; Genomic instability in cancers; Oncogenes; BRCA-mutation

Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Cardiovascular mechanics, how the heart and blood vessels respond to mechanical forces

Key words
biomechanics, artery, elastin, matrix

Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Cancer Biology
Neurosciences

Research summary
We study how the major microtubule organizing center of animal cells, the centrosome, is formed and regulated to enable cell division and signaling

Key words
Centrosomes, cilia, microtubules, cytoskeleton, organelles, subcellular organization, cell dynamics, mitosis, cell cycle, cell biology, biochemistry

Program affiliation
Biochemistry Biophysics and Structural Biology
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis

Research summary
Antibiotic drug discovery

Key words

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Cell Biology

Research summary
The Whelan laboratory studies the biology of negative-strand (NS) RNA viruses, divided between two major areas of focus: viral gene expression and viral-host cell interactions.

Key words