Biochemistry Biophysics and Structural Biology
Jonathan Silva, PhD
Associate Professor
- Email: jonsilva@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Biomedical Informatics and Data Science
Research summary
Engineering to help cardiac arrhythmia patients feel better and live longer.
Key words
Bioelectricity, Arrhythmias, Modeling, Molecular Imaging, Electrophysiology, Induced Pluripotent Stem Cells
Srikanth Singamaneni, PhD
Associate Professor
- Email: singamaneni@WUSTL.EDU
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Plasmonic biosensors and biomimetic sensors
Key words
biomimetic sensors, plasmonic biosensors, nanostructures, transduction platforms
Nathan Singh, MD, MS
Associate Professor
- Email: nathan.singh@wustl.edu
Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding how synthetic antigen receptors direct T cell function and dysfunction in the treatment of blood cancers
Key words
CAR T cell therapy, immunotherapy for cancer, T cell signaling, T cell dysfunction, lineage decisions
Andrea Soranno, PhD
Associate Professor
- Email: soranno@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Role of disordered proteins in function and dysfunction: from Alzheimer's disease to SARS CoV 2
Key words
disordered proteins, single molecule, fluorescence, FRET, Alzheimer's disease, SARS CoV 2 nucleocapsid, Apolipoprotein E, ApoE, biomolecular condensates, polymer models
Christina Stallings, PhD
Professor
- Email: stallings@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Research summary
Molecular pathogenesis of Mycobacterium tuberculosis
Key words
bacteria, gene regulation, molecular genetics, microbiology, pathogenesis, transcription, infectious disease, innate immunity
Sheila Stewart, PhD
Professor
- Email: sheila.stewart@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Research summary
Examining the role the tumor microenvironment plays in immune modulation, tumor development, metastasis and dormancy
Key words
aging, cancer, microenvironment, RNAi, senescence, telomere
Amber Stratman, PhD
Associate Professor
- Email: a.stratman@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Research summary
The Stratman lab is broadly interested in how blood vessels form and stabilize during development, and how changes in these processes affect tissue homeostasis and disease.
Key words
mechanobiology, vascular, endothelial cell, blood flow
Eva-Maria Strauch, PhD
Associate Professor
- Email: evas@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Research summary
Key words
protein design, protein engineering, influenza, RSV, machine learning , vaccines, antivirals
Stephen Sykes, PhD
Associate Professor
- Email: s.m.sykes@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Identify and define those molecular features that drive leukemogenesis and then use that information to develop rational therapeutic strategies for improving outcomes in acute leukemia
Key words
leukemia, metabolism, therapy resistance, stem cells
Simon Tang, PhD
Associate Professor
- Email: simon.tang@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
The biological regulation of skeletal matrix quality
Key words