Biochemistry Biophysics and Structural Biology


Jennifer Wang, PhD
Assistant Professor
- Email: wjennifer@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Cancer Biology
Neurosciences
Research summary
We study how the major microtubule organizing center of animal cells, the centrosome, is formed and regulated to enable cell division and signaling
Key words
Centrosomes, cilia, microtubules, cytoskeleton, organelles, subcellular organization, cell dynamics, mitosis, cell cycle, cell biology, biochemistry

Timothy Wencewicz, PhD
Associate Professor
- Email: wencewicz@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Research summary
Antibiotic drug discovery
Key words

Sean Whelan, PhD
Marvin A. Brennecke Distinguished Professor and Head of the Department of Molecular Microbiology
- Email: spjwhelan@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Cell Biology
Research summary
The Whelan laboratory studies the biology of negative-strand (NS) RNA viruses, divided between two major areas of focus: viral gene expression and viral-host cell interactions.
Key words

David Wilson, MD, PhD
Professor
- Email: wilson_d@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Role of transcription factors in differentiation and development
Key words
embryonic development, lung development, mouse models, transcriptional regulation

Jinbin Xu, PhD
Associate Professor
- Email: jinbinxu@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology
Cancer Biology
Research summary
Alzheimer’s disease, Parkinson's disease, central nervous disorders, postmortem biomarker validation and characterization, in vivo positron emission tomography, in vitro quantitative autoradiography
Key words
Imaging, biomarkers, cancer, neuroscience, PET, quantitative autoradiography, pharmaceuticals, biological assays, human brain function and disease

Lan Yang, PhD
Associate Professor
- Email: lyang25@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
We develop various light-wave based technologies, such as novel sensors, spectroscopy and imaging systems, for biological and medical applications.
Key words
nanotechnology, photonics, material physics, biosensing, spectroscopy, imaging

Jason Yi, PhD
Assistant Professor
- Email: jasonyi@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding the mechanisms of nervous system construction and dysfunction.
Key words

Zhongsheng You, PhD
Professor
- Email: zyou@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Cancer Biology
Research summary
DNA and RNA surveillance mechanisms and their relation to cancer formation and treatment
Key words
cancer, replication stress response, DNA damage response, nonsense-mediated RNA decay, genetically-encoded reporters, cell imaging

Peng Yuan, PhD
Associate Professor
- Email: yuanp@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Molecular mechanisms of membrane transport
Key words
Cryo-electron microscopy, X-ray crystallography, electrophysiology, membrane proteins, ion channels, ion transporters