Cancer Biology
Sidharth Puram, MD, PhD
Lindburg Professor and Head of the Department of Otolaryngology
- Email: sidpuram@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Computational and Systems Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Understanding the role of tumor heterogeneity in cancer biology, including its contributions to cancer development, growth, metastasis, and treatment resistance mechanisms, in order to translate these insights into new diagnostics and novel therapeutics
Key words
tumor heterogeneity; single cell; spatial transcriptomics; head and neck cancer; signaling
Lee Ratner, MD, PhD
Professor
- Email: lratner@wustl.edu
Program affiliation
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Research summary
Molecular biology and pathogenesis of HIV and HTLV
Key words
lymphocytes, virology, AIDS, leukemia, HIV, HTLV, NF kB
Patricia Ribeiro Pereira, PhD
Assistant Professor
- Email: ribeiropereirap@wustl.edu
Program affiliation
Cancer Biology
Research summary
Molecular imaging tools to understand tumor biology and response to therapies
Key words
cancer, imaging, therapy, antibody, membrane receptors, radiochemistry
Linda Richards, AO, FAA, FAHMS, PhD
Edison Professor of Neuroscience & Head of the Department of Neuroscience
- Email: neurosciencechair@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Cancer Biology
Molecular Cell Biology
Research summary
The Brain Development and Disorders Laboratory investigates how long-range neural circuits are established in the brain, and how neural circuit plasticity affects the function of the cerebral cortex.
Key words
cognitive and behavioral neuroscience, developmental neurobiology, molecular and cellular neuroscience, neurogenetics, cerebral cortex, corpus callosum, glial development, neuronal development, brain wiring, agenesis
Eduardo Rosa-Molinar, PhD
Professor
Program affiliation
Cancer Biology
Neurosciences
Developmental Regenerative and Stem Cell Biology
Biomedical Informatics and Data Science
Research summary
Key words
Robert Schreiber, PhD
Alumni Endowed Professor
- Email: rdschreiber@wustl.edu
Program affiliation
Immunology
Cancer Biology
Research summary
Cytokine receptor signaling and immunological protection against tumor development
Key words
cancer, lymphocyte, cytokine, signal transduction, tumor editing
Julie Schwarz, MD, PhD
Professor and Vice Chair of Research
- Email: jschwarz@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Research summary
Studying cancer therapy resistance mechanisms in humans and preclinical models
Key words
Tumor metabolism, glycolysis, glutaminolysis, imaging, microenvironment, HPV, immunology, radiation therapy
Jieya Shao, PhD
Associate Professor
- Email: shao.j@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Research summary
Molecular mechanisms and therapeutic potential of novel cancer targets
Key words
cancer, genome stability, targeted therapy, proteostasis, autophagy, DNA replication stress, DNA damage response, phosphorylation
Kooresh Shoghi, PhD
Professor
- Email: shoghik@wustl.edu
Program affiliation
Computational and Systems Biology
Cancer Biology
Biomedical Informatics and Data Science
Neurosciences
Research summary
I have multidisciplinary research interests spanning disease biology, engineering, imaging sciences, and informatics. Our work integrates computational imaging, artificial intelligence, and clinical/translational medicine to discover and validate quantitative imaging biomarkers and to define therapeutic endpoints in cancer and other diseases.
Key words
Computational medicine, cancer, systems biology and quantitative imaging
Monica Shokeen, PhD
Associate Professor
- Email: shokeenm@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases
Key words