Cancer Biology
Russell Pachynski, MD
Associate Professor
- Email: rkpachynski@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Research summary
Key words
Hua Pan, PhD
Associate Professor
- Email: hpan@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
https://sites.wustl.edu/panlab/
Key words
Onco-Nephrology, Cardio-Oncology, Cancer, MRI, Gene/drug delivery, Machine Learning
Yikyung Park, MS/ScD
Associate Professor
- Email: yikyungpark@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Research summary
Key words
Nutrition, Cancer, Epidemiology, Risk prediction, Population health
Bhuvic Patel, MD
Assistant Professor
- Email: bhuvic.patel@wustl.edu
Program affiliation
Neurosciences
Cancer Biology
Computational and Systems Biology
Research summary
Our lab employs cutting-edge molecular biology techniques to investigate the genetic, epigenetic, and cellular alterations driving the initiation, progression, and therapeutic resistance of brain tumors.
Key words
brain tumors, systems biology, genetics, neurosurgery, neurooncology
Gary Patti, PhD
Michael and Tana Powell Professor
- Email: gjpattij@wustl.edu
Program affiliation
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
To understand the metabolic crosstalk between cells and tissues in disease models such as cancer by using isotopes and metabolomics
Key words
metabolism, metabolomics, mass spectrometry, bioinformatics, imaging, cancer, tumor microenvironment, isotope tracing
Jacqueline Payton, MD, PhD
Associate Professor
- Email: jpayton@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Biomedical Informatics and Data Science
Molecular Microbiology and Microbial Pathogenesis
Research summary
Epigenomic aberrations in B cell lymphomas and their impact on gene regulation
Key words
epigenomics, cancer, lymphoma, histone, informatics, genomics, gene regulation
Guangyong Peng, MD, PhD
Professor
- Email: pengg@wustl.edu
Program affiliation
Immunology
Cancer Biology
Neurosciences
Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.
Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy
Stephen Persaud, MD,PhD
Assistant Professor
- Email: persaud@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Research summary
Optimizing hematopoietic stem cell transplantation as definitive therapy for non-malignant blood diseases
Key words
sickle cell disease, hematopoietic stem cell transplantation, antibody-based immunotherapy, conditioning, JAK inhibitors, gene editing
Sidharth Puram, MD, PhD
Lindburg Professor and Head of the Department of Otolaryngology
- Email: sidpuram@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Computational and Systems Biology
Immunology
Developmental Regenerative and Stem Cell Biology
Research summary
Understanding the role of tumor heterogeneity in cancer biology, including its contributions to cancer development, growth, metastasis, and treatment resistance mechanisms, in order to translate these insights into new diagnostics and novel therapeutics
Key words
tumor heterogeneity; single cell; spatial transcriptomics; head and neck cancer; signaling
Lee Ratner, MD, PhD
Professor
- Email: lratner@wustl.edu
Program affiliation
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Research summary
Molecular biology and pathogenesis of HIV and HTLV
Key words
lymphocytes, virology, AIDS, leukemia, HIV, HTLV, NF kB