Cancer Biology

Program affiliation
Cancer Biology

Research summary
Molecular imaging tools to understand tumor biology and response to therapies

Key words
cancer, imaging, therapy, antibody, membrane receptors, radiochemistry

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Cancer Biology
Molecular Cell Biology

Research summary
The Brain Development and Disorders Laboratory investigates how long-range neural circuits are established in the brain, and how neural circuit plasticity affects the function of the cerebral cortex.

Key words
cognitive and behavioral neuroscience, developmental neurobiology, molecular and cellular neuroscience, neurogenetics, cerebral cortex, corpus callosum, glial development, neuronal development, brain wiring, agenesis

Program affiliation
Cancer Biology
Neurosciences
Developmental Regenerative and Stem Cell Biology
Biomedical Informatics and Data Science

Research summary

Key words

Program affiliation
Immunology
Cancer Biology

Research summary
Cytokine receptor signaling and immunological protection against tumor development

Key words
cancer, lymphocyte, cytokine, signal transduction, tumor editing

Program affiliation
Cancer Biology
Molecular Cell Biology

Research summary
Studying cancer therapy resistance mechanisms in humans and preclinical models

Key words
Tumor metabolism, glycolysis, glutaminolysis, imaging, microenvironment, HPV, immunology, radiation therapy

Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
Molecular mechanisms and therapeutic potential of novel cancer targets

Key words
cancer, genome stability, targeted therapy, proteostasis, autophagy, DNA replication stress, DNA damage response, phosphorylation

Program affiliation
Computational and Systems Biology
Cancer Biology
Biomedical Informatics and Data Science
Neurosciences

Research summary
I have multidisciplinary research interests spanning disease biology, engineering, imaging sciences, and informatics. Our work integrates computational imaging, artificial intelligence, and clinical/translational medicine to discover and validate quantitative imaging biomarkers and to define therapeutic endpoints in cancer and other diseases.

Key words
Computational medicine, cancer, systems biology and quantitative imaging

Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Immunology

Research summary
Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases

Key words

Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology

Research summary
Long non-coding RNAs and RNA modifications in cancer metastasis and aggressive disease

Key words
Cancer metastasis, multiple myeloma, breast cancer, long non-coding RNAs, RNA modifications, genomics, advanced sequencing, epitranscriptomics

Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology

Research summary
Understanding how synthetic antigen receptors direct T cell function and dysfunction in the treatment of blood cancers

Key words
CAR T cell therapy, immunotherapy for cancer, T cell signaling, T cell dysfunction, lineage decisions