Cancer Biology
Tanner Johanns, MD, PhD
Assistant Professor
- Email: tannerjohanns@wustl.edu
Program affiliation
Immunology
Cancer Biology
Research summary
Novel immunotherapeutic strategies to treat solid tumors
Key words
Yoon A Kang, PhD
Assistant Professor
- Email: yoonakang@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology
Research summary
Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose
Key words
Hematopoietic stem cells, Multipotent progenitors, Cell fate decision, Lineage specification, Stem cell biology, Cancer (myeloid leukemia), Aging
Vaishali Kapoor, PhD
Assistant Professor
- Email: vkapoor@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology
Research summary
A major component of my research program is to (1) develop strategies for improving the therapeutic ratio of radiation therapy by increasing tumor sensitivity to radiation and limiting normal tissue toxicity and (2) understand the biological mechanisms of treatment resistance.
Key words
Cancer targeting, antibodies, Translational research, Radiation, Lung Cancer, Glioblastoma, Signaling mechanisms
Charles Kaufman, MD, PhD
Associate Professor
- Email: ckkaufman@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding and modifying the mechanisms controlling the onset of melanoma cancer by integrating zebrafish models and human disease
Key words
melanoma, cancer initiation, epigenetics, molecular genetics, neural crest, zebrafish, cancer models
Dineo Khabele, MD
Mitchell & Elaine Yanow Professor & Head of the Department of Obstetrics and Gynecology
- Email: khabeled@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
clinical and translational research in gynecologic oncology, with a focus on ovarian cancer
Key words
Albert Kim, MD, PhD
Associate Professor
- Email: alberthkim@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Cancer Biology
Research summary
Genetic and epigenetic changes that drive malignant behavior in brain tumors
Key words
brain tumors, glioblastoma, meningioma, neural stem cells
Miriam Kim, MD
Assistant Professor
- Email: miriamykim@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Research summary
My goal is to understand how CAR T cells interact with their immune environment, and to manipulate these interactions to improve outcomes of treatment.
Key words
CAR T cells, HSCs, cell therapy, gene therapy, cancer
Eynav Klechevsky, PhD
Assistant Professor
- Email: eklechevsky@wustl.edu
Program affiliation
Immunology
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
understand the biology of different human dendritic cells and other myeloid cells as a key for manipulating immune responses in various disease conditions
Key words
Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines
John Krais, PhD
Assistant Professor
- Email: krais@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Our laboratory focuses on the fundamental issues of DNA repair and how they relate to cancer initiation, progression, and therapy responses.
Key words
DNA repair, DNA replication
Timothy Ley, MD
Lewis T. and Rosalind B. Apple Chair in Oncology
- Email: timley@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Immunology
Cancer Biology
Research summary
Study of normal versus leukemic blood cell development and immunology
Key words
cancer genomics, leukemia, oncogene