Cancer Biology
Joseph Ippolito, MD, PhD
Associate Professor
- Email: ippolitoj@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Neurosciences
Research summary
Precision medicine through metabolism-based imaging and therapy: from laboratory to clinical translation
Key words
cancer, metabolism, imaging, sex differences, body composition
James W. Janetka, PhD
Professor
- Email: janetkaj@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Cancer Biology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
The rational structure-based drug design and synthesis for cancer and infectious disease
Key words
protease, kinase, cancer, infection, lectin, chemistry, synthesis, drug discovery, peptidomimetic, inhibitor
Shu (Joy) Jiang, PhD
Assistant Professor
- Email: jiang.shu@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Cancer Biology
Research summary
Development of novel statistical methods for precision medicine
Key words
Biostatistics; Image analysis; Dynamic risk prediction; Multistate models
Ramon Jin, MD,PhD
Assistant Professor
- Email: jinr@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Cancer Biology
Research summary
I am interested in precursor conditions or metaplasias in the stomach and esophagus (i.e Barrett’s esophagus) as these lesions are key to understanding the formation of gastroesophageal adenocarcinomas.
Key words
Intestinal metaplasia, gastroesophageal cancer, Barrett's esophagus, GI development, Organoids
Tanner M. Johanns, MD, PhD
Assistant Professor
- Email: tannerjohanns@wustl.edu
Program affiliation
Immunology
Cancer Biology
Research summary
Novel immunotherapeutic strategies to treat solid tumors
Key words
Yoon A Kang, PhD
Assistant Professor
- Email: yoonakang@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology
Research summary
Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose
Key words
Hematopoietic stem cells, Multipotent progenitors, Cell fate decision, Lineage specification, Stem cell biology, Cancer (myeloid leukemia), Aging
Vaishali Kapoor, PhD
Assistant Professor
- Email: vkapoor@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology
Research summary
A major component of my research program is to (1) develop strategies for improving the therapeutic ratio of radiation therapy by increasing tumor sensitivity to radiation and limiting normal tissue toxicity and (2) understand the biological mechanisms of treatment resistance.
Key words
Cancer targeting, antibodies, Translational research, Radiation, Lung Cancer, Glioblastoma, Signaling mechanisms
Sana D. Karam, MD, PhD
James S McDonnell Professor & Chair of the Department of Radiation Oncology
- Email: sanadkaram@wustl.edu
Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
tumor growth, metastasis, signaling mechanisms, immunology, cancer, B cells, Tregs
Charles Kaufman, MD, PhD
Associate Professor
- Email: ckkaufman@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding and modifying the mechanisms controlling the onset of melanoma cancer by integrating zebrafish models and human disease
Key words
melanoma, cancer initiation, epigenetics, molecular genetics, neural crest, zebrafish, cancer models
Dineo Khabele, MD
Mitchell & Elaine Yanow Professor & Head of the Department of Obstetrics and Gynecology
- Email: khabeled@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
clinical and translational research in gynecologic oncology, with a focus on ovarian cancer
Key words