Cancer Biology
Fuhai Li, PhD
Associate Professor
- Email: fuhai.li@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Cancer Biology
Research summary
Integrative large-scale pharmaco genomics analysis for target, signaling network, drug and drug combination discovery. Genomics data driven tumor-stromal communication discovery and modeling.
Key words
Yang Li, PhD
Assistant Professor
- Email: yeli@wustl.edu
Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Cancer Biology
Neurosciences
Research summary
Our research interests include developing innovative computational tools/methods and utilizing single-cell (epi)genomic techniques to gain a comprehensive understanding of gene regulation in mammalian models and human diseases, particularly in brain tumors and neuropsychiatric disorders.
Key words
Bioinformatics, Gene Regulation, Single-cell Epigenetics, Brain Tumors, Neurological Disorders
Kian Lim, MD, PhD
Associate Professor
- Email: kian-huat.lim@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Research summary
Understanding the role of inflammation in gastrointestinal cancers
Key words
NF-kB, Toll-like receptors, IRAK4, TAK1, KRAS, ERK, MK2
Daniel Link, MD
Alan and Edith Wolff Professor of Medicine
- Email: dlink@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Regulation of normal and malignant hematopoiesis
Key words
Leukemia, clonal hematopoiesis, stem cells, niche, ribosome, cancer metabolism, neutrophils, genomics
Gregory Longmore, MD
Professor
- Email: glongmore@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology
Research summary
Cell Motility and Cancer Metastasis
Key words
cell motility, cancer metastasis, cell adhesion, signal transduction
Jeffrey Magee, MD, PhD
Associate Professor
- Email: mageej@wustl.edu
Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Developmental context and genetic variation as underlying mechanisms of childhood cancer
Key words
Cancer biology, stem cell, hematopoiesis, leukemia, developmental biology
Kiran Mahajan, PhD
Assistant Professor
- Email: kiranm@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
Nupam Mahajan, PhD
Professor
- Email: nupam@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Cancer Biology
Research summary
How tyrosine phosphorylation regulates epigenetic processes that affect cellular homeostasis and cancer cell survival
Key words
Christopher Maher, PhD
Associate Professor
- Email: christophermaher@wustl.edu
Program affiliation
Cancer Biology
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Research summary
Translational Cancer Genomics; Noncoding RNAs
Key words
non-coding RNAs, lncRNAs, cancer genomics, transcriptome, bioinformatics, computational biology, solid tumor malignancies
Michael Major, PhD
Alan A. and Edith L. Wolff Professor
- Email: bmajor@wustl.edu
Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Research summary
Studying how perturbation of specific signal transduction pathways contributes to the initiation, progression and dissemination of cancer
Key words
proteomics, functional genomics, lung cancer, signal transduction, WNT, oxidative stress