Cancer Biology
John Olson Jr., MD, PhD
William K. Bixby Professor and Head of the Department of Surgery
- Email: jaolson@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Research summary
Understanding endocrine tumor formation
Key words
Russell Pachynski, MD
Associate Professor
- Email: rkpachynski@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Research summary
Key words
Bhuvic Patel, MD
Assistant Professor
- Email: bhuvic.patel@wustl.edu
Program affiliation
Neurosciences
Cancer Biology
Computational and Systems Biology
Research summary
Our lab employs cutting-edge molecular biology techniques to investigate the genetic, epigenetic, and cellular alterations driving the initiation, progression, and therapeutic resistance of brain tumors.
Key words
brain tumors, systems biology, genetics, neurosurgery, neurooncology
Gary Patti, PhD
Michael and Tana Powell Professor
- Email: gjpattij@wustl.edu
Program affiliation
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
To understand the metabolic crosstalk between cells and tissues in disease models such as cancer by using isotopes and metabolomics
Key words
metabolism, metabolomics, mass spectrometry, bioinformatics, imaging, cancer, tumor microenvironment, isotope tracing
Jacqueline Payton, MD, PhD
Associate Professor
- Email: jpayton@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Biomedical Informatics and Data Science
Molecular Microbiology and Microbial Pathogenesis
Research summary
Epigenomic aberrations in B cell lymphomas and their impact on gene regulation
Key words
epigenomics, cancer, lymphoma, histone, informatics, genomics, gene regulation
Guangyong Peng, MD, PhD
Professor
- Email: pengg@wustl.edu
Program affiliation
Immunology
Cancer Biology
Neurosciences
Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.
Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy
Stephen Persaud, MD,PhD
Assistant Professor
- Email: persaud@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Research summary
Optimizing hematopoietic stem cell transplantation as definitive therapy for non-malignant blood diseases
Key words
sickle cell disease, hematopoietic stem cell transplantation, antibody-based immunotherapy, conditioning, JAK inhibitors, gene editing