Cancer Biology

Program affiliation
Cancer Biology
Biochemistry Biophysics and Structural Biology
Immunology

Research summary
https://sites.wustl.edu/panlab/

Key words
Onco-Nephrology, Cardio-Oncology, Cancer, MRI, Gene/drug delivery, Machine Learning

Program affiliation
Biomedical Informatics and Data Science
Cancer Biology

Research summary

Key words
Nutrition, Cancer, Epidemiology, Risk prediction, Population health

Program affiliation
Neurosciences
Cancer Biology
Computational and Systems Biology

Research summary

Key words

Program affiliation
Cancer Biology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science

Research summary
To understand the metabolic crosstalk between cells and tissues in disease models such as cancer by using isotopes and metabolomics

Key words
metabolism, metabolomics, mass spectrometry, bioinformatics, imaging, cancer, tumor microenvironment, isotope tracing

Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Biomedical Informatics and Data Science
Molecular Microbiology and Microbial Pathogenesis

Research summary
Epigenomic aberrations in B cell lymphomas and their impact on gene regulation

Key words
epigenomics, cancer, lymphoma, histone, informatics, genomics, gene regulation

Program affiliation
Immunology
Cancer Biology
Neurosciences

Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.

Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy

Program affiliation
Molecular Genetics and Genomics
Cancer Biology
Computational and Systems Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Understanding the role of tumor heterogeneity in cancer biology, including its contributions to cancer development, growth, metastasis, and treatment resistance mechanisms, in order to translate these insights into new diagnostics and novel therapeutics

Key words
tumor heterogeneity; single cell; spatial transcriptomics; head and neck cancer; signaling

Program affiliation
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics

Research summary
Molecular biology and pathogenesis of HIV and HTLV

Key words
lymphocytes, virology, AIDS, leukemia, HIV, HTLV, NF kB

Program affiliation
Cancer Biology

Research summary
Molecular imaging tools to understand tumor biology and response to therapies

Key words
cancer, imaging, therapy, antibody, membrane receptors, radiochemistry

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Cancer Biology
Molecular Cell Biology

Research summary
The Brain Development and Disorders Laboratory investigates how long-range neural circuits are established in the brain, and how neural circuit plasticity affects the function of the cerebral cortex.

Key words
cognitive and behavioral neuroscience, developmental neurobiology, molecular and cellular neuroscience, neurogenetics, cerebral cortex, corpus callosum, glial development, neuronal development, brain wiring, agenesis