Computational and Systems Biology
Hema Adhikari, PhD
Assistant Professor
- Email: hema.adhikari@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Cancer Biology
Computational and Systems Biology
Molecular Cell Biology
Research summary
Key words
Maxim Artyomov, PhD
Associate Professor
- Email: martyomov@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology
Research summary
Systems immunology using high-throughput next-generation sequencing in conjunction with mathematical and statistical modeling approaches rooted in statistical physics
Key words
systems immunology, systems biology, computational biology, RNA-seq
Megan Baldridge, MD, PhD
Associate Professor
- Email: mbaldridge@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Computational and Systems Biology
Research summary
Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity
Key words
microbiota, infection, pathogen, microbiome, virus, interferon, immunity
Ivan Baxter, PhD
Member
- Email: ibaxter@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Computational and Systems Biology
Research summary
We use quantitative genetics and high throughput phenotyping approaches to understand how plants adapt to their environment
Key words
Ionomics, Genetics, Genomics, Gene by Environment Interactions, Plants
Michael Belloy, PhD
Assistant Professor
- Email: belloy@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Research summary
Our research is dedicated to understanding the genetics of Alzheimer’s disease and related disorders, employing bioinformatic tools and a big-data approach that integrates genetics, multi-omics, brain imaging, and clinical data.
Key words
Genetics, Multi-Omics, Bioinformatics, Neurodegeneration, Alzheimer's disease
Janine Bijsterbosch, PhD
Assistant Professor
Program affiliation
Neurosciences
Biomedical Informatics and Data Science
Computational and Systems Biology
Research summary
Computational neuroimaging using big data to study brain organization and mental health
Key words
mental health, fMRI, connectivity, big data, psychiatry, computational models
Kelly Bolton, MD, PhD
Assistant Professor
- Email: bolton@wustl.edu
Program affiliation
Human and Statistical Genetics
Computational and Systems Biology
Cancer Biology
Research summary
The interplay between inherited genetic variation, environmental factors, and acquired mutations in shaping the earliest stages of carcinogenesis
Key words
cancer, genetics, computational biology, genetic epidemiology
Arpita Bose, PhD
Associate Professor
- Email: abose@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
Microbial metabolisms and their influence on biogeochemical cycling
Key words
Michael Brent, PhD
Professor
- Email: brent@wustl.edu
Program affiliation
Computational and Systems Biology
Human and Statistical Genetics
Molecular Genetics and Genomics
Research summary
Computational genomics, human genetics, systems biology, transcriptional regulatory networks
Key words
computational biology, systems biology, regulatory circuits, computational genomics, multi-omics integration, human genetics
Jeremy Buhler, PhD
Professor
- Email: jbuhler@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Developing algorithms and architectures for large-scale biosequence comparison, genome annotation, and metagenomics
Key words
annotation, bioinformatics, computational biology, genome analysis, metagenomics