Developmental Regenerative and Stem Cell Biology
Aki Ushiki, PhD
Assistant Professor
- Email: akiu@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Computational and Systems Biology
Molecular Cell Biology
Research summary
Our lab investigates how non-coding genetic variation controls developmental programs and contributes to human disease and evolutionary change. We focus on congenital structural anomalies, pregnancy complications, and bat wing development, combining mouse genetics, embryo genome engineering, and functional genomics approaches, including in vivo MPRAs, to functionally dissect regulatory elements.
Key words
Enhancers, non-coding regulatory variation, developmental genetics, evolution, GWAS, limb development, placental biology, craniofacial development, functional genomics, MPRA
Steven Van Dyken, PhD
Associate Professor
- Email: svandyken@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Cytokine-mediated tissue feedback loops that maintain homeostasis, and environmental factors that instigate inflammation and fibrosis.
Key words
Qian Wang, PhD
Assistant Professor
- Email: w.qian@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
We use mouse genetics to study signaling networks that control eye development and homeostasis
Key words
lens, lacrimal gland, signaling, FGF, mTOR
Mark Warchol, PhD
Professor
- Email: mwarchol@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Research summary
Mechanisms of development, injury and repair in the vertebrate auditory system
Key words
hearing, vestibular, sensory, development, regeneration, macrophage, microglia
Philip Williams, PhD
Assistant Professor
- Email: prwillia@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Research summary
Strategies to improve outcomes of nervous system injury and disease, regeneration and preservation
Key words
Andrew Yoo, PhD
Professor
- Email: yooa@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Neurosciences
Research summary
Generation of human neurons by direct cell fate reprogramming and modeling late-onset neurodegenerative disorders
Key words
neurodegeneration, neurogenesis, microRNA, cellular reprogramming, disease modeling, chromatin, regenerative medicine
Mohamed Zayed, MD,PhD
Professor
- Email: zayedm@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
The mechanisms that influence arterial collateral formation and peripheral arterial atheroprogression in the setting of diabetes
Key words
Bo Aber Zhang
Assistant Professor
- Email: bzhang29@wustl.edu
Program affiliation
Computational and Systems Biology
Biomedical Informatics and Data Science
Developmental Regenerative and Stem Cell Biology
Research summary
Key words
Bioinformatics, epigenetics
Chao Zhou, PhD
Associate Professor
- Email: chaozhou@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Research summary
Developing novel optical imaging technologies for biomedical applications including cancer research and tissue engineering
Key words
Biophotonics, medical instrumentation, imaging sciences, optical coherence tomography (OCT) and microscopy (OCM) and optogenetic pacing