Developmental Regenerative and Stem Cell Biology
Lawrence Salkoff, PhD
Professor
- Email: salkoffl@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
How ion channels function in physiology and behavior
Key words
neurobiology, genome analysis, development, behavior, physiology
Tim Schedl, PhD
Professor
- Email: ts@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Research summary
Control of germline stem cells and meiotic development in C. elegans
Key words
germ cells, C. elegans, genetics, development, functional genomics
Erica Scheller, DDS, PhD
Assistant Professor
- Email: scheller@wustl.edu
Program affiliation
Molecular Cell Biology
Neurosciences
Developmental Regenerative and Stem Cell Biology
Research summary
Interactions between the nervous system and the skeleton
Key words
bone, diabetes, nerve, neuropathy, neuroskeletal biology, obesity, metabolism, adipose tissue, adipocyte, high-resolution imaging, advanced quantification, RNAseq, regeneration, healing
Laura Schuettpelz, MD, PhD
Professor
- Email: schuettpelz_l@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Immunology
Molecular Genetics and Genomics
Research summary
Regulation of hematopoietic stem cells (HSCs) by inflammation
Key words
Lori Setton, PhD
Professor & Chair
- Email: setton@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Understanding the mechanisms for degeneration and regeneration of soft tissues of the musculoskeletal system, including the intervertebral disc, articular cartilage, and meniscus
Key words
Lavinia Sheets, PhD
Associate Professor
- Email: sheetsl@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
We use zebrafish as a model for human hearing and balance with the goal of protecting and repairing inner ears from damage.
Key words
zebrafish, sensory neuroscience, hearing, balance, synaptic physiology, regeneration
Jie Shen, PhD
Associate Professor
- Email: shen.j@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Focused on injury, repair, and regeneration of musculoskeletal tissues with the goal to understand the progenitor cell population, signals, and role of inflammation on tissue injury and regeneration at the cellular and molecular level
Key words
Mengcheng Shen
Assistant Professor
- Email: shen.m@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Immunology
Neurosciences
Research summary
My research program integrates cardiovascular physiology, stem cell biology, developmental biology, functional genomics, and cardio-oncology to investigate molecular mechanisms of congenital and acquired cardiovascular diseases. My laboratory specializes in developing innovative protocols for generating authentic cardiovascular cell types from human induced pluripotent stem cells (iPSCs), advancing cardiovascular precision medicine. We aim to bridge basic science and clinical translation through disease modeling, therapeutic target identification, and adverse outcome prevention.
Key words
iPSC, CRISPR, organoid, cardiovascular, precision medicine, cardio-oncology
Lilianna Solnica-Krezel, PhD
Professor and Head of the Department of Developmental Biology
- Email: solnical@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Research summary
Inductive and morphogenetic processes that establish and shape germ layers during vertebrate embryogenesis, using zebrafish and embryonic stem cell models
Key words
Gastrulation, Vertebrate embryogenesis, Patterning, Cell movement, Cell signaling, Morphogenesis, Stem Cells