Developmental Regenerative and Stem Cell Biology

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
I am interested in studying the cellular and molecular mechanisms by which gut mycobiota (fungi) modulates local and systemic health with a goal to develop better biomarkers and therapeutic approaches.

Key words

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Cancer Biology

Research summary
I am interested in precursor conditions or metaplasias in the stomach and esophagus (i.e Barrett’s esophagus) as these lesions are key to understanding the formation of gastroesophageal adenocarcinomas.

Key words
Intestinal metaplasia, gastroesophageal cancer, Barrett's esophagus, GI development, Organoids

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Immunology

Research summary
Molecular mechanisms of skeletal and cardiac muscle development and disease

Key words
muscle, congenital disease, organogenesis, gene discovery

Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology

Research summary
Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose

Key words
Hematopoietic stem cells, Multipotent progenitors, Cell fate decision, Lineage specification, Stem cell biology, Cancer (myeloid leukemia), Aging

Program affiliation
Neurosciences
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Understanding the molecular and cellular mechanisms underlying tauopathies

Key words
neurodegeneration, neurogenetics, Alzheimer`s disease, frontotemporal dementia, tau, amyloid precursor protein, induced pluripotent stem cells (iPSC), cell and molecular biology, molecular mechanisms

Program affiliation
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
Understanding and modifying the mechanisms controlling the onset of melanoma cancer by integrating zebrafish models and human disease

Key words
melanoma, cancer initiation, epigenetics, molecular genetics, neural crest, zebrafish, cancer models

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology

Research summary
Visual system neuroscience and vision restoration

Key words
physiology, imaging, behavior, genetic and viral engineering, human neuroscience, vision, repair, mathematical modeling

Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Mitochondria and autophagy in ischemic liver injury and liver aging

Key words
mitochondria, liver, fatty liver disease

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology

Research summary
My goal is to understand how CAR T cells interact with their immune environment, and to manipulate these interactions to improve outcomes of treatment.

Key words
CAR T cells, HSCs, cell therapy, gene therapy, cancer

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
We are fundamentally interested in the complex cellular and molecular interactions that take place during joint homeostasis and disease.

Key words
Osteoarthritis, Immunology, Crosstalk, Fibrosis, Inflammation