Developmental Regenerative and Stem Cell Biology
Kristen L. Kroll, PhD
Professor
- Email: kkroll@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Neurosciences
Research summary
Transcriptional and epigenetic regulation of neural development and its dysregulation to cause neurodevelopmental disorders
Key words
human pluripotent stem cell, autism, neuron, neurodevelopmental disorders, cerebral organoid, epigenetic regulation, transcriptional regulation, neurobiology, embryonic stem cell, neural stem cell, transcription, gene regulatory network, chromatin, embryo
Tristan Li, PhD
Assistant Professor
- Email: qingyunli@wustl.edu
Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
Microglial biology and neuro-immune interactions in development, aging and disease
Key words
microglia, neuroimmunology, development, aging, neurodegeneration, single cell
Xiaowei Li, PHD
Assistant Professor
- Email: xiaoweili@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Developmental Regenerative and Stem Cell Biology
Neurosciences
Research summary
The Li laboratory is dedicated to developing biomaterial platforms for regenerative medicine, specifically focusing on applications in angiogenesis, vascularization, stem cell engineering, and tissue regeneration.
Key words
Biomaterials, Tissue Engineering, Regenerative Medicine
Ta-Chiang Liu, MD, PhD
Professor
- Email: ta-chiang.liu@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understanding how host genetics and environmental factors interact to shape gut metabolism leading to inflammation and epithelial differentiation defect
Key words
Irfan J. Lodhi, PhD
Associate Professor
- Email: ilodhi@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Research summary
We seek to understand how specialized lipid pathways regulate thermogenesis, energy balance, and metabolic health, and how disruption of these pathways contributes to obesity, diabetes, fatty liver disease, and cardiovascular disease.
Key words
Adipose tissue, brown fat, diabetes, obesity, lipid metabolism, peroxisomes, mitochondria
Liang Ma, PhD
Associate Professor
- Email: lima@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Understanding genetic pathways regulating epithelial differentiation
Key words
development, differentiation, cell signaling, gene expression, genetics
Jeffrey Magee, MD, PhD
Elizabeth H. and James S. McDonnell III Professor
- Email: mageej@wustl.edu
Program affiliation
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Causes and new approaches to curing high-risk pediatric leukemia
Key words
Cancer biology, stem cell, hematopoiesis, leukemia, developmental biology
Moe Mahjoub, PhD
Associate Professor
- Email: mmahjoub@wustl.edu
Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
The microtubule cytoskeleton in health and disease
Key words
Cell cytoskeleton, microtubules, cilia, centrosome, cell cycle, signal transduction, kidney/lung development and disease
Gabriel Mbalaviele, PhD
Professor
- Email: gmbalaviele@wustl.edu
Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Role of inflammasomes in disease
Key words
Inflammation, Inflammasomes, Skeleton, Cytokines