Developmental Regenerative and Stem Cell Biology
Audrey McAlinden, PhD
Associate Professor
- Email: mcalindena@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Research summary
Molecular mechanisms regulating skeletal development
Key words
microRNAs; stem cells; skeletal development and regeneration; cartilage; chondrocyte differentiation; pre-mRNA alternative splicing
Helen McNeill, PhD
Professor and BJC Investigator
- Email: mcneillh@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Cancer Biology
Molecular Genetics and Genomics
Research summary
Coordinating cell proliferation and cell organization in organ development
Key words
Michael Meers, PhD
Assistant Professor
- Email: meers@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Understanding the molecular determinants of cellular diversity
Key words
Chromatin, Transcription Factors, Epigenomics, Cell fate, Single-cell
Gretchen A. Meyer, PhD
Associate Professor
- Email: meyerg@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Research summary
Understanding how changes at the molecular and cellular level in skeletal muscle affect muscle structure and function
Key words
Craig Micchelli, PhD
Associate Professor
- Email: micchelli@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Research summary
The biology of stem cells
Key words
cancer, Drosophila, regeneration, stem cells
Jeffrey Milbrandt, MD, PhD
James S. McDonnell Professor
- Email: jmilbrandt@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Axonal degeneration, regulation of myelination, neuronal energetics and mitochondrial function in neuropathy and neurodegenerative disease
Key words
functional genomics, metabolism, mitochondria, diabetic neuropathy, neurodegeneration, transcriptional networks, Alzheimer’s disease, Schwann cell
Jeffrey R. Millman, PhD
Professor
- Email: jmillman@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Differentiation to and maturation of pancreatic insulin-producing β cells from human pluripotent stem cells capable of rapidly reversing diabetes
Key words
stem cell biology, regeneration, developmental biology, microscopy, single-cell RNA-sequencing, differentiation, tissue engineering, diabetes, organoids, transplantation, therapy
Mayssa H. Mokalled, PhD
Associate Professor
- Email: mmokalled@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Neurosciences
Molecular Genetics and Genomics
Research summary
Mechanisms of neural regeneration and astrocyte reactivity using zebrafish, mouse, and human models.
Key words
regeneration, spinal cord injury, nervous system repair, astrocytes, glia, neurons, plasticity
Kenneth M. Murphy, MD, PhD
Eugene Opie First Centennial Professor
- Email: kmurphy@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Dendritic cell development and diversification
Key words
Dendritic cell and T cell differentiation, gene expression, transcription, inflammation
Arin D. Oestreich, PhD
Assistant Professor
- Email: aoestreich@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
Our laboratory investigates how early-life exposures influence skeletal development and long-term musculoskeletal health, with the goal of defining targetable cellular and molecular mechanisms to guide the development of therapeutic interventions.
Key words
women's health, orthopedics, developmental origins of health and disease, osteoarthritis, genetic diseases