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Arpana Agrawal, PhD

Associate Professor

Program affiliation
Human and Statistical Genetics

Research summary
Genetic and environment studies of addictions

Key words

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John Atkinson, MD

Professor

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Human and Statistical Genetics

Research summary
Complement activation and regulation in innate and adaptive immunity

Key words
immunology, inflammation, autoimmunity, complement system, innate immunity

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Laura Bierut, MD

Professor

Program affiliation
Human and Statistical Genetics
Biomedical Informatics and Data Science

Research summary
Family and genetic studies of psychiatric illnesses and substance dependence (alcoholism, smoking, and cocaine dependence)

Key words
alcoholism, genetics, substance abuse

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Ryan Bogdan, PhD

Associate Professor

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Human and Statistical Genetics

Research summary
How genetic variation and environmental experience contribute to individual differences in brain function, behavior, and psychopathology

Key words

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Kelly Bolton, MD, PhD

Assistant Professor

Program affiliation
Human and Statistical Genetics
Computational and Systems Biology
Cancer Biology

Research summary
The interplay between inherited genetic variation, environmental factors, and acquired mutations in shaping the earliest stages of carcinogenesis

Key words
cancer, genetics, computational biology, genetic epidemiology

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Michael Brent, PhD

Professor

Program affiliation
Computational and Systems Biology
Human and Statistical Genetics
Molecular Genetics and Genomics

Research summary
Computational genomics, human genetics, systems biology, transcriptional regulatory networks

Key words
computational biology, systems biology, regulatory circuits, computational genomics, multi-omics integration, human genetics

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F. Sessions Cole, MD

Park J. White Professor

Program affiliation
Human and Statistical Genetics
Developmental Regenerative and Stem Cell Biology

Research summary
Genetic lung disease, Surfactant protein B, and rare diseases in infants

Key words
functional genomics, bioinformatics, pulmonary surfactant, lung development

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Megan Cooper, MD, PhD

Anthony R. French, MD, PhD, Professor

Program affiliation
Immunology
Human and Statistical Genetics

Research summary
The Cooper laboratory is focused on investigating the molecular and immunologic basis of inborn errors of immunity. We are particularly interested in understanding novel genetic causes of these diseases in children with immune dysregulation syndromes.

Key words
inborn errors of immunity, genetics, primary immunodeficiency STAT3, TLR8, Pediatrics

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Sharon Cresci, MD

Associate Professor

Program affiliation
Human and Statistical Genetics
Computational and Systems Biology
Molecular Genetics and Genomics

Research summary
Genetic variation in the variable response to pharmacologic treatment (i.e. Pharmacogenomics) of cardiovascular disease; specifically individuals with both diabetes mellitus and coronary artery disease.

Key words
cardiovascular disease, diabetes melitus, genotype, genetic variation

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Carlos Cruchaga, PhD

Barbara Burton & Reuben Morriss III Professor

Program affiliation
Human and Statistical Genetics
Neurosciences
Biomedical Informatics and Data Science
Molecular Genetics and Genomics

Research summary
The goal of my lab is to understand the biology of neurodegeneration by using high-dimensional omic data and functional genomic approaches.

Key words
Neurodegeneration, Alzheimer, genetics, genomics, proteomics, system biology, molecular phenotyping, functional genomics