Immunology

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Biochemistry Biophysics and Structural Biology

Research summary
Respiratory immunobiology, with particular interest in cytokine pathways associated with lung epithelial progenitors

Key words

Program affiliation
Immunology
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Molecular mechanisms at the host-pathogen interface

Key words
biochemistry, structural biology, signaling, virology, host pathogen interactions, immunology

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology

Research summary
Our research investigates the role of the innate immune system in the pathogenesis of neurodegenerative diseases and the processes of brain aging, employing stem cell-based platforms and transgenic mouse models to study mechanisms of neuroimmune interactions in the brain.

Key words
Neurodegeneration, Innate Immunity, Aging

Program affiliation
Immunology
Computational and Systems Biology
Biochemistry Biophysics and Structural Biology

Research summary
Systems immunology using high-throughput next-generation sequencing in conjunction with mathematical and statistical modeling approaches rooted in statistical physics

Key words
systems immunology, systems biology, computational biology, RNA-seq

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Computational and Systems Biology

Research summary
Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity

Key words
microbiota, infection, pathogen, microbiome, virus, interferon, immunity

Program affiliation
Immunology
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology

Research summary
Immunometabolism - metabolic regulation of immune cell activation

Key words

Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Immunology

Research summary
Our research is focused on soft tissue biomechanics and mechanobiology

Key words

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Emerging viruses

Key words
Host-pathogen interactions, Influenza virus, SARS-CoV-2, Bourbon virus, Viral pathogenesis, RNA biology, Influenza Reassortment

Program affiliation
Immunology
Molecular Cell Biology
Neurosciences

Research summary
Understanding how immune cells and metabolic organs interact to maintain normal metabolism and to support adaptation to physiologic challenges

Key words
Immunometabolism, Mitochondria, White/beige/brown adipose tissue, Innate immunity, Macrophages, Obesity

Program affiliation
Biochemistry Biophysics and Structural Biology
Immunology

Research summary
The molecular basis of lung diseases and drug development using structural biology tools

Key words
biophysics, crystallography, molecular medicine, asthma, mucosal immunology, Alzheimer`s disease, endocytosis, receptor trafficking, structural biology, structure based drug design