Immunology

Program affiliation
Immunology
Cancer Biology
Molecular Cell Biology

Research summary
Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.

Key words

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Innate and Adaptive Host Immunity to Viral Infections

Key words
virology, microbial pathogenesis, immunology

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Cell Biology

Research summary
Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine

Key words

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Immune cell development and function

Key words
dendritic cells, macrophages, hematopoiesis, infection, inflammation, innate immunity, autoimmunity, multiple sclerosis

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology

Research summary
Gene regulation for lymphocyte development and adaptive immune responses

Key words
lymphocyte development, adaptive immunity, transcription factors, cytokines, oncogenesis

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.

Key words

Program affiliation
Molecular Cell Biology
Immunology
Cancer Biology

Research summary
interactions between bone and immune cells in inflammation and cancer

Key words
arthritis, inflammation, cancer, bone metastases, osteoclasts

Program affiliation
Immunology
Cancer Biology

Research summary
My laboratory is focused on the molecular mechanisms regulating natural killer cell activation, novel methods to use NK cells as immunotherapy for cancer, and lymphoma genomics.

Key words
cancer, cytokine, immunology, innate immunity, NK cells, small noncoding RNAs, immunotherapy, lymphoma, genomics

Program affiliation
Immunology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
We are examining the role of the autophagy pathway in the function of the retina and its role in diseases of the eye

Key words
angiogenesis, apoptosis, autophagy, immunology, lymphocyte, tolerance, photoreceptors, vision,

Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Molecular Genetics and Genomics

Research summary
We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.

Key words