Immunology
Megan Cooper, MD, PhD
Anthony R. French, MD, PhD, Professor
- Email: cooper_m@wustl.edu
Program affiliation
Immunology
Human and Statistical Genetics
Research summary
The Cooper laboratory is focused on investigating the molecular and immunologic basis of inborn errors of immunity. We are particularly interested in understanding novel genetic causes of these diseases in children with immune dysregulation syndromes.
Key words
inborn errors of immunity, genetics, primary immunodeficiency STAT3, TLR8, Pediatrics
Richard Cote, MD
Professor and Head of the Department of Pathology and Immunology
- Email: rcote@wustl.edu
Program affiliation
Immunology
Cancer Biology
Research summary
Pathways of tumor progression and response to therapy, particularly in bladder and prostate cancer, cancer metastasis research through analysis of lymph node and bone marrow occult metastases
Key words
David Curiel, MD, PhD
Professor
- Email: dcuriel@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Developmental Regenerative and Stem Cell Biology
Research summary
To address the central mandate of gene therapy we engineer adenovirus tropism to allow the achievement of effective gene delivery
Key words
Adenovirus, virotherapy, virus, cancer, gene therapy, vaccine
Mai Dang, MD, PhD
Assistant Professor
- Email: mai@wustl.edu
Program affiliation
Neurosciences
Cancer Biology
Immunology
Research summary
The primary research goal of our laboratory is to uncover novel ways to alter the pediatric brain tumor microenvironment to enhance the efficacy of existing treatments and make treatments safer for children.
Key words
brain tumors, cancer, neurology, immunology, imaging
Albert Davis, MD, PhD
Assistant Professor
- Email: albert.a.davis@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
Key words
David DeNardo, PhD
Professor
- Email: ddenardo@WUSTL.EDU
Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Research summary
Molecular Mechanisms of Immune Regulation of Tumor Progression.
Key words
immunotherapy, breast cancer, pancreatic cancer, immunology, inflammation, metastasis, storm
Carl DeSelm, MD, PhD
Assistant Professor
- Email: deselmc@wustl.edu
Program affiliation
Immunology
Cancer Biology
Molecular Cell Biology
Research summary
Dr. DeSelm clinically focuses on treating lymphoma, and is actively developing novel CAR T cell approaches to treating solid tumors, including lymphoma, pancreatic cancer and glioblastoma.
Key words
Michael Diamond, MD, PhD
Herbert S. Gasser Professor
- Email: mdiamond@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
Innate and Adaptive Host Immunity to Viral Infections
Key words
virology, microbial pathogenesis, immunology
Siyuan Ding, PhD
Associate Professor
- Email: siyuan.ding@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Cell Biology
Research summary
Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
Key words
Brian Edelson, MD, PhD
Associate Professor
- Email: bedelson@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Immune cell development and function
Key words
dendritic cells, macrophages, hematopoiesis, infection, inflammation, innate immunity, autoimmunity, multiple sclerosis