Immunology

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Innate and Adaptive Host Immunity to Viral Infections

Key words
virology, microbial pathogenesis, immunology, vaccines, therapeutics, antibody

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Cell Biology

Research summary
Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine

Key words

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics

Research summary
Immune cell development and function

Key words
dendritic cells, macrophages, hematopoiesis, infection, inflammation, innate immunity, autoimmunity, multiple sclerosis

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology

Research summary
Gene regulation for lymphocyte development and adaptive immune responses

Key words
lymphocyte development, adaptive immunity, transcription factors, cytokines, oncogenesis

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.

Key words

Program affiliation
Molecular Cell Biology
Immunology
Cancer Biology

Research summary
interactions between bone and immune cells in inflammation and cancer

Key words
arthritis, inflammation, cancer, bone metastases, osteoclasts

Program affiliation
Immunology
Cancer Biology

Research summary
My laboratory is focused on the molecular mechanisms regulating natural killer cell activation, novel methods to use NK cells as immunotherapy for cancer, and lymphoma genomics.

Key words
cancer, cytokine, immunology, innate immunity, NK cells, small noncoding RNAs, immunotherapy, lymphoma, genomics

Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Molecular Genetics and Genomics

Research summary
We use both mouse models and patient samples of acute myloid leukemia to understand leukemogenesis and to identify novel therapeutic targets.

Key words

Program affiliation
Computational and Systems Biology
Immunology
Cancer Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science

Research summary
My research interests lie in integrating and applying novel computational biology techniques with mechanistic experimental immunology to understand drivers of response and resistance to NK cell therapies for cancer

Key words
natural killer cells, computational biology, single-cell sequencing, immunotherapy, nk cells

Program affiliation
Biochemistry Biophysics and Structural Biology
Cancer Biology
Neurosciences
Immunology
Developmental Regenerative and Stem Cell Biology

Research summary
Small molecule drug discovery inspired research across multiple therapeutic areas including chronic pain, oncology, and neurodegeneration.

Key words
drug discovery, medicinal chemistry, chemical biology, synthetic methods