Immunology

Program affiliation
Immunology
Computational and Systems Biology

Research summary
Studying effects of dysregulated nutrients in the tumor microenvironment on anti-tumor immunity.

Key words
immunometabolism, tumor immunology, polyamine transport

Program affiliation
Cancer Biology
Immunology

Molecular Cell Biology

Research summary
Advancing knowledge of the mechanisms responsible for colorectal tumor progression, with a specific focus on Stress and its influence on the Tumor Microenvironment.

Key words
Tumor Microenvironment, Stress

Program affiliation
Cancer Biology
Immunology

Research summary

Key words

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology

Research summary
New drugs for post-viral and related types of disease

Key words
drug discovery, innate immunity, epithelial stem cells, viruses, respiratory airway disease

Program affiliation
Cancer Biology
Immunology

Research summary
Understanding T cell tolerance to self and non-self

Key words
autoimmunity, immunology, lymphocyte, regulatory T cell, tolerance, mucosal immunology

Program affiliation
Immunology
Cancer Biology

Research summary
Novel immunotherapeutic strategies to treat solid tumors

Key words

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Immunology

Research summary
Molecular mechanisms of skeletal and cardiac muscle development and disease

Key words
muscle, congenital disease, organogenesis, gene discovery

Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology

Research summary
Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose

Key words
Hematopoietic stem cells, Multipotent progenitors, Cell fate decision, Lineage specification, Stem cell biology, Cancer (myeloid leukemia), Aging

Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology

Research summary
A major component of my research program is to (1) develop strategies for improving the therapeutic ratio of radiation therapy by increasing tumor sensitivity to radiation and limiting normal tissue toxicity and (2) understand the biological mechanisms of treatment resistance.

Key words
Cancer targeting, antibodies, Translational research, Radiation, Lung Cancer, Glioblastoma, Signaling mechanisms

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Microbial community-immune interactions in airway diseases and urogenital tract

Key words
microbiota; microbiome; mucosal immunity; asthma; allergy; atopy; urinary tract infection; pathogen colonization; metabolomics;