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Sana D. Karam, MD, PhD

James S McDonnell Professor & Chair of the Department of Radiation Oncology

Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary

Key words
tumor growth, metastasis, signaling mechanisms, immunology, cancer, B cells, Tregs

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Andrew L. Kau, MD, PhD

Associate Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Microbial community-immune interactions in airway diseases and urogenital tract

Key words
microbiota; microbiome; mucosal immunity; asthma; allergy; atopy; urinary tract infection; pathogen colonization; metabolomics;

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Peggy L. Kendall, MD

Virginia Minnich Distinguished Professor

Program affiliation
Immunology

Research summary
The role of B lymphocytes in autoimmune disease

Key words

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Miriam Kim, MD

Assistant Professor

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Cancer Biology

Research summary
My goal is to understand how CAR T cells interact with their immune environment, and to manipulate these interactions to improve outcomes of treatment.

Key words
CAR T cells, HSCs, cell therapy, gene therapy, cancer

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Jonathan Kipnis, PhD

BJC Investigator & Alan A. and Edith L. Wolff Distinguished Professor

Program affiliation
Immunology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology

Research summary
We study complex interactions between the immune and nervous systems in health and disease

Key words
Neuroimmunology; neuroscience; immunology; lymphatics; behavior; Alzheimer’s disease; neurodegeneration; glia; microglia; blood-brain barrier (BBB); meninges

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Eynav Klechevsky, PhD

Associate Professor

Program affiliation
Immunology
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology

Research summary
understand the biology of different human dendritic cells and other myeloid cells as a key for manipulating immune responses in various disease conditions

Key words
Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines

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Alexander Knights, PhD

Assistant Professor

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics

Research summary
We are fundamentally interested in the complex cellular and molecular interactions that take place during joint homeostasis and disease.

Key words
Osteoarthritis, Immunology, Crosstalk, Fibrosis, Inflammation

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Dmitri Kotov, PhD

Assistant Professor

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology

Research summary
My lab works on the host immune response to Mycobacterium tuberculosis. We use mouse models that mimic key aspects of human disease to gain a mechanistic understanding of the host response allowing for the identification of novel targets for host-directed therapies.

Key words
Mycobacterium tuberculosis, innate immunology, macrophages, neutrophils, dendritic cells

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Daniel Kreisel, MD, PhD

Professor

Program affiliation
Immunology
Molecular Cell Biology

Research summary

Key words

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Brian Laidlaw, PhD

Assistant Professor

Program affiliation
Immunology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Investigating the development of immunological memory in disease states

Key words
B cells, immunological memory, germinal center, virus, allergy