Immunology
Michael J. Holtzman, MD
Selma and Herman Seldin Professor
- Email: mjholtzman@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Research summary
New drugs for post-viral and related types of disease
Key words
drug discovery, innate immunity, epithelial stem cells, viruses, respiratory airway disease
Chyi-Song Hsieh, MD, PhD
Professor
- Email: chsieh@wustl.edu
Program affiliation
Cancer Biology
Immunology
Research summary
Understanding T cell tolerance to self and non-self
Key words
autoimmunity, immunology, lymphocyte, regulatory T cell, tolerance, mucosal immunology
Eric J. Huang, MD, PhD
Joseph M. Davie Distinguished Professor and Chair of the Department of Pathology and Immunology
- Email: erichuang@wustl.edu
Program affiliation
Immunology
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
Tanner M. Johanns, MD, PhD
Assistant Professor
- Email: tannerjohanns@wustl.edu
Program affiliation
Immunology
Cancer Biology
Research summary
Novel immunotherapeutic strategies to treat solid tumors
Key words
Aaron Johnson, PhD
Associate Professor
- Email: anjohnson@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Immunology
Research summary
Molecular mechanisms of skeletal and cardiac muscle development and disease
Key words
muscle, congenital disease, organogenesis, gene discovery
Yoon A Kang, PhD
Assistant Professor
- Email: yoonakang@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology
Research summary
Decoding cell fate decision mechanisms to modulate lineage output for therapeutic purpose
Key words
Hematopoietic stem cells, Multipotent progenitors, Cell fate decision, Lineage specification, Stem cell biology, Cancer (myeloid leukemia), Aging
Usheer Kanjee, PhD
Assistant Professor
- Email: kanjee@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Immunology
Molecular Genetics and Genomics
Research summary
We are broadly interested in understanding host/pathogen interactions in malaria parasites. We use a range of approaches including biochemistry, red blood cell genetics and parasite genetics to identify essential ligand/receptor interactions in malaria parasites, with the long-term goal of developing novel therapeutics.
Key words
malaria, red blood cell, plasmodium, ligand/receptor
Vaishali Kapoor, PhD
Assistant Professor
- Email: vkapoor@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology
Research summary
A major component of my research program is to (1) develop strategies for improving the therapeutic ratio of radiation therapy by increasing tumor sensitivity to radiation and limiting normal tissue toxicity and (2) understand the biological mechanisms of treatment resistance.
Key words
Cancer targeting, antibodies, Translational research, Radiation, Lung Cancer, Glioblastoma, Signaling mechanisms
Sana D. Karam, MD, PhD
James S McDonnell Professor & Chair of the Department of Radiation Oncology
- Email: sanadkaram@wustl.edu
Program affiliation
Immunology
Cancer Biology
Computational and Systems Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Key words
tumor growth, metastasis, signaling mechanisms, immunology, cancer, B cells, Tregs
Andrew L. Kau, MD, PhD
Associate Professor
- Email: akau@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Genetics and Genomics
Computational and Systems Biology
Research summary
Microbial community-immune interactions in airway diseases and urogenital tract
Key words
microbiota; microbiome; mucosal immunity; asthma; allergy; atopy; urinary tract infection; pathogen colonization; metabolomics;