Immunology
Janet Lee, MD
Selma and Herman Seldin Distinguished Professor
- Email: ljanet@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Key words
Deborah Lenschow, MD, PhD
John S. Daniels Professor
- Email: dlenschow@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases
Key words
host-pathogen interactions, immunology, innate immunity, interferons, pathogenesis, virology, autoimmune disease, lupus
Timothy Ley, MD
Lewis T. and Rosalind B. Apple Chair in Oncology
- Email: timley@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Immunology
Cancer Biology
Research summary
Study of normal versus leukemic blood cell development and immunology
Key words
cancer genomics, leukemia, oncogene
Kian Lim, MD, PhD
Associate Professor
- Email: kian-huat.lim@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Research summary
Understanding the role of inflammation in gastrointestinal cancers
Key words
NF-kB, Toll-like receptors, IRAK4, TAK1, KRAS, ERK, MK2
Daniel Link, MD
Alan and Edith Wolff Professor of Medicine
- Email: dlink@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Regulation of normal and malignant hematopoiesis
Key words
Leukemia, clonal hematopoiesis, stem cells, niche, ribosome, cancer metabolism, neutrophils, genomics
Ta-Chiang Liu, MD, PhD
Associate Professor
- Email: ta-chiang.liu@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understanding how host genetics and environmental factors interact to shape gut metabolism leading to inflammation
Key words
Gregory Longmore, MD
Professor
- Email: glongmore@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Immunology
Research summary
Cell Motility and Cancer Metastasis
Key words
cell motility, cancer metastasis, cell adhesion, signal transduction
Carolina Lopez, PhD
Professor and BJC Investigator
- Email: clopezzalaquett@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
The Lopez Lab studies how viruses interact with the body and how defective viruses influence the development of diseases in humans
Key words
virus, respiratory syncytial virus, Sendai virus, innate immunity, antiviral immunity
Kiran Mahajan, PhD
Assistant Professor
- Email: kiranm@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
My laboratory studies the pathogenic role of epigenetic regulators in prostate cancer development and progression, with a focus on the mechanisms by which these factors co-operate with transcription factors to drive tumor heterogeneity and resistance to various standard of care therapies
Key words
Epigenetics, prostate cancer, transcriptomics, small molecule therapeutics, radioresistance, DNA damage signaling, tumor-immune dynamics.
Melissa Mavers, MD,PhD
Assistant Professor
- Email: mmmavers@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Cancer Biology
Research summary
Harnessing immune cells to prevent acute graft-versus-host disease
Key words
innate lymphocytes, graft-versus-host disease, cell therapies, cancer