Immunology
Alexander Knights, PhD
Assistant Professor
- Email: aknights@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
We are fundamentally interested in the complex cellular and molecular interactions that take place during joint homeostasis and disease.
Key words
Osteoarthritis, Immunology, Crosstalk, Fibrosis, Inflammation
Dmitri Kotov, PhD
Assistant Professor
- Email: kotov@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
My lab works on the host immune response to Mycobacterium tuberculosis. We use mouse models that mimic key aspects of human disease to gain a mechanistic understanding of the host response allowing for the identification of novel targets for host-directed therapies.
Key words
Mycobacterium tuberculosis, innate immunology, macrophages, neutrophils, dendritic cells
Daniel Kreisel, MD, PhD
Professor
- Email: kreiseld@WUSTL.EDU
Program affiliation
Immunology
Molecular Cell Biology
Research summary
Key words
Brian Laidlaw, PhD
Assistant Professor
- Email: brian.laidlaw@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Investigating the development of immunological memory in disease states
Key words
B cells, immunological memory, germinal center, virus, allergy
Kory Lavine, MD, PhD
Professor
- Email: klavine@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Immunology
Molecular Cell Biology
Research summary
Identify signaling pathways that mediate cardiac tissue repair/regeneration and heart failure pathogenesis.
Key words
heart failure, heart development, macrophages, innate immunity
Janet Lee, MD
Selma and Herman Seldin Distinguished Professor
- Email: ljanet@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Key words
Deborah Lenschow, MD, PhD
John S. Daniels Professor
- Email: dlenschow@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Antiviral mechanisms of type I interferons and the role of interferons and viruses in autoimmune diseases
Key words
host-pathogen interactions, immunology, innate immunity, interferons, pathogenesis, virology, autoimmune disease, lupus
Timothy Ley, MD
Lewis T. and Rosalind B. Apple Chair in Oncology
- Email: timley@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Immunology
Cancer Biology
Research summary
Study of normal versus leukemic blood cell development and immunology
Key words
cancer genomics, leukemia, oncogene
Kian Lim, MD, PhD
Associate Professor
- Email: kian-huat.lim@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Cell Biology
Research summary
Understanding the role of inflammation in gastrointestinal cancers
Key words
NF-kB, Toll-like receptors, IRAK4, TAK1, KRAS, ERK, MK2
Daniel Link, MD
Alan and Edith Wolff Professor of Medicine
- Email: dlink@wustl.edu
Program affiliation
Cancer Biology
Immunology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Regulation of normal and malignant hematopoiesis
Key words
Leukemia, clonal hematopoiesis, stem cells, niche, ribosome, cancer metabolism, neutrophils, genomics