Molecular Cell Biology
Malay Choudhury, PhD
Assistant Professor
- Email: malay@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Our current research focuses on delineating the cellular, molecular, and metabolic processes involved in the development of fibrotic disorders such as Idiopathic pulmonary fibrosis (IPF) and how these metabolic adaptations may in turn be targeted therapeutically for IPF.
Key words
Idiopathic pulmonary fibrosis (IPF), metabolic networks, targetable mechanisms driving fibroblast function and fibrosis
Matthew Christopher, MD, PhD
Assistant Professor
- Email: christopherm@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Improve outcomes for patients with acute myeloid leukemia (AML) and other hematopoietic malignancies utilizing genomic and molecular biology techniques
Key words
Roberto Civitelli, MD
Professor
- Email: civitellir@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Cancer Biology
Research summary
Connexins, cadherins in bone cell interactions with cancer and energy metabolism
Key words
bone biology, cell adhesion, signal transduction, gap junctions, cadherin
Regina Clemens, MD, PhD
Assistant Professor
- Email: clemensra@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Research summary
The mechanisms regulating calcium-dependent neutrophil activation
Key words
Clair Crewe, PhD
Assistant Professor
- Email: clair.crewe@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding extracellular vesicle (EV)-mediated signaling during homeostatic and pathologic metabolic regulation
Key words
Yifan Dai, PhD
Assistant Professor
- Email: dyifan@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Research summary
My lab aims to establish the fundamental principles of intracellular physical chemistry and electrochemical functions of macromolecular complexes, and design synthetic proteins as therapeutics for condensate-dependent diseases.
Key words
molecular biology; physical chemistry; biochemistry; biophysics; synthetic biology; electrochemistry; phase transition; condensates
Zhiyu Dai, PhD
Associate Professor
- Email: z.dai@wustl.edu
Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
My research aims to understand the lung vascular homeostasis and the pathogenesis of pulmonary diseases using novel animal models, integrated pharmacological approaches, genome editing and single cell RNA-sequencing and spatial transcriptomics.
Key words
cardiovascular, lung, vascular, single cell, spatial transcriptomic
Nicholas Davidson, MD
Professor
- Email: nod@wustl.edu
Program affiliation
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
Mammalian gene expression: Regulation through mRNA editing and RNA stabilization
Key words
gene expression, RNA, cancer, mRNA editing, mRNA stability
Albert Davis, MD, PhD
Assistant Professor
- Email: albert.a.davis@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Immunology
Biochemistry Biophysics and Structural Biology
Research summary
Understanding the molecular and cellular mechanisms of protein aggregation and neurodegeneration in Parkinson disease and dementia with Lewy bodies
Key words
David DeNardo, PhD
Professor
- Email: ddenardo@WUSTL.EDU
Program affiliation
Cancer Biology
Molecular Cell Biology
Immunology
Research summary
Molecular Mechanisms of Immune Regulation of Tumor Progression.
Key words
immunotherapy, breast cancer, pancreatic cancer, immunology, inflammation, metastasis, storm