Molecular Cell Biology
Leslie Gewin, MD
Associate Professor
- Email: gewin@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Mechanisms of chronic kidney disease progression, treatment options to halt kidney disease progression
Key words
Aliereza Ghanbarpour, PhD
Assistant Professor
- Email: alirezag@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology
Computational and Systems Biology
Research summary
Our research focuses on unraveling the molecular mechanisms underlying substrate specificity and degradation by AAA proteolytic machines and their associated adaptor proteins, utilizing structural biology, biochemistry, and cellular assays in both bacteria and human mitochondria.
Key words
AAA proteases, cryo-EM, biochemistry, mass spectrometry, structural biology, microbiology, mitochondria
Daniel Goldberg, MD, PhD
Professor
- Email: dgoldberg@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Biochemistry of malaria
Key words
biochemistry, metabolism, parasitology, malaria, protease, heme, aspartic
Dennis Goldfarb, PhD
Assistant Professor
- Email: d.goldfarb@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Computational mass spectrometry and proteomics
Key words
Mass Spectrometry, Proteomics, Bioinformatics
Nardhy Gomez-Lopez, PhD
Professor
- Email: nardhy@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Computational and Systems Biology
Research summary
Our research is dedicated to investigating the immunobiological pathways that underlie such pregnancy complications, with a special emphasis on preterm birth.
Key words
Immunology of Pregnancy, Maternal-fetal Immunology, In utero Inflammation, Preterm Birth
Vivian Gonzalez-Perez, PhD
Assistant Professor
- Email: gonzalez-perez.v@wustl.edu
Program affiliation
Molecular Cell Biology
Neurosciences
Research summary
Key words
Matthew Goodwin, MD, PhD
Assistant Professor
- Email: matthewlgoodwin@wustl.edu
Program affiliation
Molecular Cell Biology
Cancer Biology
Molecular Genetics and Genomics
Research summary
Metabolism of cancer, targeting tumor metabolism by blocking metabolic pathways
Key words
Jeffrey Gordon, MD
Dr. Robert J. Glaser Distinguished University Professor
- Email: jgordon@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Molecular Cell Biology
Plant and Microbial Biosciences
Research summary
Role of the human gut microbiome in health and disease, notably childhood undernutrition and obesity
Key words
Gut microbiome; systems biology; postnatal development; childhood malnutrition; global health; gnotobiotic animal models; metabolic regulation; food webs; gut-brain axis; gut barrier/immune function; microbiome-targeted therapeutics
Gary Grajales, MD,PhD
Assistant Professor
- Email: ggary@wustl.edu
Program affiliation
Immunology
Neurosciences
Biomedical Informatics and Data Science
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Key words
Gregory Grant, PhD
Professor
- Email: ggrant@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Relationship of structure to function in allosteric control mechanisms
Key words
protein structure, protein function, allosteric regulation, enzymology, biochemistry