Molecular Genetics and Genomics

Program affiliation
Ecology and Evolutionary Biology
Plant and Microbial Biosciences
Molecular Genetics and Genomics

Research summary
The evolution of sociality, cooperation, and cheating in a eukaryotic microbe, using experimental evolution, genomics, and other approaches

Key words
social interactions, evolution, microbiology, social amoebae, kin selection, moleuclar evolution, multicellularity, development, genomics

Program affiliation
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics

Research summary
Molecular biology and pathogenesis of HIV and HTLV

Key words
lymphocytes, virology, AIDS, leukemia, HIV, HTLV, NF kB

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics

Research summary
Investigate gene regulation during kidney development and disease

Key words

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Cancer Biology
Molecular Cell Biology

Research summary
The Brain Development and Disorders Laboratory investigates how long-range neural circuits are established in the brain, and how neural circuit plasticity affects the function of the cerebral cortex.

Key words
cognitive and behavioral neuroscience, developmental neurobiology, molecular and cellular neuroscience, neurogenetics, cerebral cortex, corpus callosum, glial development, neuronal development, brain wiring, agenesis

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Biomedical Informatics and Data Science

Research summary
Using bench molecular biology, high-throughput sequencing, and bioinformatics to understand human inflammatory / autoimmune disease.

Key words
human genetics; autoimmune; inflammatory disease; biomarkers; high-throughput sequencing; precision medicine

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Statistical genetics, complex human diseases, analysis methods

Key words
genetics, substance dependence, addiction, human disease gene mapping, association studies, linkage analysis

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
How ion channels function in physiology and behavior

Key words
neurobiology, genome analysis, development, behavior, physiology

Program affiliation
Neurosciences
Molecular Genetics and Genomics
Computational and Systems Biology

Research summary
Intersection between visceral sensation, organ function, and emotions

Key words
Visceral Pain, Genomics, Neural Circuits, Emotions

Program affiliation
Molecular Genetics and Genomics
Neurosciences
Molecular Cell Biology

Research summary
Pathophysiology and novel therapies for lysosomal storage diseases

Key words
gene therapy, hematopoiesis, metabolism, neurobiology, neurodegeneration, stem cells

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology

Research summary
My laboratory uses genetics, cell biology and systems biology approaches to study how the cell regulates its metabolic programs and how dysfunctions in these programs lead to neurological disease

Key words