Molecular Genetics and Genomics
Zhiyu Dai, PhD
Associate Professor
- Email: z.dai@wustl.edu
Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Research summary
My research aims to understand the lung vascular homeostasis and the pathogenesis of pulmonary diseases using novel animal models, integrated pharmacological approaches, genome editing and single cell RNA-sequencing and spatial transcriptomics.
Key words
cardiovascular, lung, vascular, single cell, spatial transcriptomic
Gautam Dantas, PhD
Professor
- Email: dantas@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Molecular Genetics and Genomics
Ecology and Evolutionary Biology
Biochemistry Biophysics and Structural Biology
Research summary
(1) Dynamics, ecology, and evolution of antibiotic resistance, (2) Engineering enhanced probiotics to treat GI disorders, (3) Engineering microbial biofuel catalysts
Key words
anibiotic resistance, synthetic biology, bioenergy, human microbiome, metagenomics, microbial ecology and biodiversity
Victor Davila-Roman, MD
Professor
- Email: vdavila@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Research summary
Noninvasive characterization of heart function in patients with high blood pressure
Key words
imaging, hypertrophy, myocardial bloodflow
Jorge Di Paola, MD
Professor/Division Chief
- Email: dipaolaj@wustl.edu
Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
The genetics of bleeding and thrombotic disorders and mechanisms of platelet activation
Key words
Li Ding, PhD
David English Smith Distinguished Professor
- Email: lding@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Cancer Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Cancer Proteogenomics and Cancer Models
Key words
Joseph Dougherty, PhD
Professor
- Email: jdougherty@wustl.edu
Program affiliation
Neurosciences
Molecular Genetics and Genomics
Computational and Systems Biology
Human and Statistical Genetics
Research summary
Human Psychiatric Genetics, Mouse Models, Cell Type Specific Gene Expression Profiling, Translation, Astrocytes.
Key words
autism, gene expression profiling, genetics, genomics, mouse models, neurobiology, astrocytes, translation regulation
Susan Dutcher, PhD
Professor
- Email: dutcher@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Molecular Cell Biology
Human and Statistical Genetics
Plant and Microbial Biosciences
Research summary
Key words
centrioles, cilia, signal transduction, cytoskeleton,
John Edwards, PhD
Associate Professor
- Email: jredwards@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics
Research summary
We develop new computational and experimental approaches to understand the roles of DNA methylation and hydroxymethylation in neurodevelopment and cancer
Key words
bioinformatics, cancer, cancer genomics, epigenetics, epigenomics, neurodevelopment, transcriptional regulation