Molecular Genetics and Genomics
Charles Kaufman, MD, PhD
Associate Professor
- Email: ckkaufman@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
Understanding and modifying the mechanisms controlling the onset of melanoma cancer by integrating zebrafish models and human disease
Key words
melanoma, cancer initiation, epigenetics, molecular genetics, neural crest, zebrafish, cancer models
Andreas Kautt, PhD
Assistant Professor
- Email: kautt@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Neurosciences
Molecular Genetics and Genomics
Research summary
In the Kautt Lab, we combine a genomics-centered approach with molecular experiments, behavioral assays, and fieldwork to elucidate both the evolutionary and molecular mechanisms underlying organismal adaptation and diversification, with a focus on animal behavior.
Key words
Evolution, Genomics, Behavior, Adaptation, Speciation
Dineo Khabele, MD
Mitchell & Elaine Yanow Professor & Head of the Department of Obstetrics and Gynecology
- Email: khabeled@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
clinical and translational research in gynecologic oncology, with a focus on ovarian cancer
Key words
Albert Kim, MD, PhD
August A. Busch, Jr. Professor
- Email: alberthkim@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences
Cancer Biology
Research summary
Genetic and epigenetic changes that drive malignant behavior in brain tumors
Key words
brain tumors, glioblastoma, meningioma, neural stem cells
Jonathan Kipnis, PhD
BJC Investigator & Alan A. and Edith L. Wolff Distinguished Professor
- Email: kipnis@wustl.edu
Program affiliation
Immunology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
We study complex interactions between the immune and nervous systems in health and disease
Key words
Neuroimmunology; neuroscience; immunology; lymphatics; behavior; Alzheimer’s disease; neurodegeneration; glia; microglia; blood-brain barrier (BBB); meninges
Alexander Knights, PhD
Assistant Professor
- Email: aknights@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
We are fundamentally interested in the complex cellular and molecular interactions that take place during joint homeostasis and disease.
Key words
Osteoarthritis, Immunology, Crosstalk, Fibrosis, Inflammation
Stephen Kerry Kornfeld, MD, PhD
Professor
- Email: kornfeld@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
organismal aging; zinc homeostasis and roles of zinc during cell differentiation.
Key words
aging, metals, zinc, development, sperm activation, signal transduction, homeostasis
John Krais, PhD
Assistant Professor
- Email: krais@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Our laboratory focuses on the fundamental issues of DNA repair and how they relate to cancer initiation, progression, and therapy responses.
Key words
DNA repair, DNA replication
Barbara Kunkel, PhD
Professor
- Email: kunkel@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Research summary
Molecular genetic analysis of disease development in Pseudomonas syringae-Arabidopsis interactions
Key words
plant-microbe interactions, bacterial pathogenesis, auxin, IAA, Type III effector protein, genetics, plant biology
Michael Landis, PhD
Assistant Professor
- Email: michael.landis@wustl.edu
Program affiliation
Ecology and Evolutionary Biology
Computational and Systems Biology
Molecular Genetics and Genomics
Research summary
Modeling the evolution of species with stochastic processes [Recruiting PhD Students for Fall 2024]
Key words
phylogenetics, evolution, ecology, epidemiology, statistical models, stochastic processes, computational inference, deep learning