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Gaya Amarasinghe, PhD

Alumni Endowed Professor

Program affiliation
Immunology
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Molecular mechanisms at the host-pathogen interface

Key words
biochemistry, structural biology, signaling, virology, host pathogen interactions, immunology

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Beau Ances, MD, PhD

Daniel J. Brennan Professor

Program affiliation
Neurosciences
Molecular Microbiology and Microbial Pathogenesis
Biomedical Informatics and Data Science

Research summary
Characterization of Dementia (HIV associated neurocognitive disorders (HAND) and Alzheimer`s Disease (AD) using functional magnetic resonance imaging

Key words
Alzheimer’s disease, blood flow, brain mapping, dementia, HIV, MRI

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Megan Baldridge, MD, PhD

Associate Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Computational and Systems Biology

Research summary
Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity

Key words
microbiota, infection, pathogen, microbiome, virus, interferon, immunity

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Joshua Blodgett, PhD

Associate Professor

Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis

Research summary
Interdisciplinary questions surrounding bacterial small molecule production

Key words
Streptomyces, biosynthesis, genome mining, antibiotics, regulation & genetics

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Adrianus Boon, PhD

Associate Professor

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Emerging viruses

Key words
Host-pathogen interactions, Influenza virus, SARS-CoV-2, Bourbon virus, Viral pathogenesis, RNA biology, Influenza Reassortment

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Arpita Bose, PhD

Associate Professor

Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology

Research summary
Microbial metabolisms and their influence on biogeochemical cycling

Key words

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Juliane Bubeck Wardenburg, MD, PhD

Professor and Chief

Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
The research in my laboratory is aimed at understanding fundamental principles of the interaction between bacterial pathogens and the human host.

Key words

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Yin Cao, ScD, MPH

Associate Professor

Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology

Research summary
Novel genetic, microbial, and lifestyle risk factors for lung and gastrointestinal cancers leveraging large-scale clinical and population-based cohorts with deep genomic and phenotypic data

Key words
Systems and translational cancer epidemiology, microbiome, inflammation and immune-metabolic networks

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Douglas Chalker, PhD

Professor

Program affiliation
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Developmental Regenerative and Stem Cell Biology

Research summary
Genetic and epigenetic regulation of developmentally programmed DNA rearrangements of Tetrahymena, control of intercellular patterning

Key words
cellular patterning, cell biology, basal bodies and cilia, chromatin structure, development, DNA, genome rearrangements, RNA interference,

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Matthew Ciorba, MD

Associate Professor

Program affiliation
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Immunology

Research summary
Tryptophan metabolism and probiotic bacteria as modifiers of intestinal cancer and inflammation

Key words
tryptophan metabolism, intestinal inflammation, colitis associated cancer, colon cancer, mucositis, tryptophan, crohn, colitis, inflammatory bowel disease, radiation enteritis