Molecular Microbiology and Microbial Pathogenesis
Gaya Amarasinghe, PhD
Alumni Endowed Professor
- Email: gamarasinghe@wustl.edu
Program affiliation
Immunology
Biochemistry Biophysics and Structural Biology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Molecular mechanisms at the host-pathogen interface
Key words
biochemistry, structural biology, signaling, virology, host pathogen interactions, immunology
Beau Ances, MD, PhD
Daniel J. Brennan Professor
- Email: bances@wustl.edu
Program affiliation
Neurosciences
Molecular Microbiology and Microbial Pathogenesis
Biomedical Informatics and Data Science
Research summary
Characterization of Dementia (HIV associated neurocognitive disorders (HAND) and Alzheimer`s Disease (AD) using functional magnetic resonance imaging
Key words
Alzheimer’s disease, blood flow, brain mapping, dementia, HIV, MRI
Megan Baldridge, MD, PhD
Associate Professor
- Email: mbaldridge@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Computational and Systems Biology
Research summary
Defining the mechanisms behind and effects of the interactions between commensal bacteria, pathogens and innate immunity
Key words
microbiota, infection, pathogen, microbiome, virus, interferon, immunity
Joshua Blodgett, PhD
Associate Professor
- Email: jblodgett@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Research summary
Interdisciplinary questions surrounding bacterial small molecule production
Key words
Streptomyces, biosynthesis, genome mining, antibiotics, regulation & genetics
Adrianus Boon, PhD
Associate Professor
- Email: jboon@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
Emerging viruses
Key words
Host-pathogen interactions, Influenza virus, SARS-CoV-2, Bourbon virus, Viral pathogenesis, RNA biology, Influenza Reassortment
Arpita Bose, PhD
Associate Professor
- Email: abose@wustl.edu
Program affiliation
Plant and Microbial Biosciences
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
Microbial metabolisms and their influence on biogeochemical cycling
Key words
Juliane Bubeck Wardenburg, MD, PhD
Professor and Chief
- Email: jbubeck@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
The research in my laboratory is aimed at understanding fundamental principles of the interaction between bacterial pathogens and the human host.
Key words
Yin Cao, ScD, MPH
Associate Professor
- Email: yin.cao@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Molecular Microbiology and Microbial Pathogenesis
Cancer Biology
Research summary
Novel genetic, microbial, and lifestyle risk factors for lung and gastrointestinal cancers leveraging large-scale clinical and population-based cohorts with deep genomic and phenotypic data
Key words
Systems and translational cancer epidemiology, microbiome, inflammation and immune-metabolic networks
Douglas Chalker, PhD
Professor
- Email: dchalker@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Developmental Regenerative and Stem Cell Biology
Research summary
Genetic and epigenetic regulation of developmentally programmed DNA rearrangements of Tetrahymena, control of intercellular patterning
Key words
cellular patterning, cell biology, basal bodies and cilia, chromatin structure, development, DNA, genome rearrangements, RNA interference,
Matthew Ciorba, MD
Associate Professor
- Email: mciorba@wustl.edu
Program affiliation
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
Tryptophan metabolism and probiotic bacteria as modifiers of intestinal cancer and inflammation
Key words
tryptophan metabolism, intestinal inflammation, colitis associated cancer, colon cancer, mucositis, tryptophan, crohn, colitis, inflammatory bowel disease, radiation enteritis