Molecular Microbiology and Microbial Pathogenesis
David Curiel, MD, PhD
Professor
- Email: dcuriel@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Genetics and Genomics
Immunology
Developmental Regenerative and Stem Cell Biology
Research summary
To address the central mandate of gene therapy we engineer adenovirus tropism to allow the achievement of effective gene delivery
Key words
Adenovirus, virotherapy, virus, cancer, gene therapy, vaccine
Yifan Dai, PhD
Assistant Professor
- Email: dyifan@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Research summary
My lab aims to establish the fundamental principles of intracellular physical chemistry and electrochemical functions of macromolecular complexes, and design synthetic proteins as therapeutics for condensate-dependent diseases.
Key words
molecular biology; physical chemistry; biochemistry; biophysics; synthetic biology; electrochemistry; phase transition; condensates
Gautam Dantas, PhD
Professor
- Email: dantas@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Research summary
(1) Dynamics, ecology, and evolution of antibiotic resistance, (2) Engineering enhanced probiotics to treat GI disorders, (3) Engineering microbial biofuel catalysts
Key words
anibiotic resistance, synthetic biology, bioenergy, human microbiome, metagenomics, microbial ecology and biodiversity
Michael Diamond, MD, PhD
Herbert S. Gasser Professor
- Email: mdiamond@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Research summary
Innate and Adaptive Host Immunity to Viral Infections
Key words
virology, microbial pathogenesis, immunology
Siyuan Ding, PhD
Associate Professor
- Email: siyuan.ding@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Immunology
Molecular Cell Biology
Research summary
Understanding how rotavirus (RV), an important enteric viral pathogen, interacts with the host innate immune system in the small intestine
Key words
Tamara Doering, MD, PhD
Alumni Endowed Professor
- Email: doering@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Molecular Cell Biology
Plant and Microbial Biosciences
Biochemistry Biophysics and Structural Biology
Research summary
Biology and pathogenesis of the pathogenic fungus Cryptococcus neoformans
Key words
biochemistry, biosynthetic pathways, cell biology, eukaryotic pathogen, gene regulation, genomic variants, glycobiology, host-pathogen interactions, microbial pathogenesis, pathogenic fungi, sterol transport, yeast
Brian Edelson, MD, PhD
Associate Professor
- Email: bedelson@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Immune cell development and function
Key words
dendritic cells, macrophages, hematopoiesis, infection, inflammation, innate immunity, autoimmunity, multiple sclerosis
Ali Ellebedy, PhD
Professor
- Email: ellebedy@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.
Key words
Mario Feldman, PhD
Professor
- Email: mariofeldman@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Plant and Microbial Biosciences
Research summary
Pathogenesis of multidrug resistant bacteria and biogenesis of bacterial vesicles in the human gut
Key words
Peter Fischer, PhD
Professor
- Email: pufischer@wustl.edu
Program affiliation
Molecular Microbiology and Microbial Pathogenesis
Research summary
Medical helminthology, especially filariasis and other neglected tropical diseases caused by parasitic worms.
Key words
helminths, parasitology, tropical medicine,