Neurosciences

Program affiliation
Neurosciences

Research summary
Understanding mechanisms contributing to individual differences in pain sensitivity and chronic pain

Key words
Pain, migraine, endometriosis, pelvic pain, sex differences, hormones, opioids, puberty, sensory testing, fMRI, pediatric pain

Program affiliation
Neurosciences
Biomedical Informatics and Data Science

Research summary
My lab focuses on developing imaging methods to characterize brain fluid compartments, tissue microstructure and neurofluid dynamics in health and disease. In addition, by perturbing brain fluid compartments, we aim to develop novel therapeutic and diagnostic approaches.

Key words
Neurofluid Imaging, Translational Neuroimaging, Preclinical MRI, CSF, Computational Neuroanatomy, Focused Ultrasound, Neurodevelopment, Neurodegenerative Disorders, Drug Delivery

Program affiliation
Molecular Cell Biology
Neurosciences
Biochemistry Biophysics and Structural Biology

Research summary
Ion channel biology in health and disease

Key words
ion channel, neurobiology, functional genomics, cell signaling, kinetics

Program affiliation
Neurosciences
Molecular Genetics and Genomics

Research summary
Molecular genetic analysis of synaptic development and function

Key words
synapse biology, genetics, Zebrafish, C. elegans, exocytosis

Program affiliation
Neurosciences

Research summary
Neurobiology at the intersections of stress, sleep, metaboslim, and sedation

Key words

Program affiliation
Neurosciences
Molecular Cell Biology

Research summary
Mechanisms underlying the specification, regulation, and neurodegeneration of dopaminergic and glutamatergic systems

Key words
apoptosis, bioinformatics, gene expression, neurobiology, signal transduction, transgenic

Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology

Research summary
Okuno Lab investigates how water molecules interact with protein surfaces and explores the underlying mechanisms of protein folding and aggregation through NMR spectroscopy.

Key words
Biophysics, NMR, solvent, protein hydration, aggregation, reverse micelles

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Neurosciences

Research summary
Regulation of lung, skeletal, and cardiovascular development, injury response, and regeneration by Fibroblast Growth Factors

Key words
cell signaling; development; fibroblast growth factors; mouse models; stem cells, regeneration; pulmonary hypertension; alveologenesis; endocrine signaling

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Computational and Systems Biology
Immunology

Research summary

Key words

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology

Research summary
My research program aims to understand the neural circuits that underlie vocal communication processing and investigate how these circuits are disrupted in neuropsychiatric disorders.

Key words
Auditory System, Neuropsychiatric Disorders, Mouse Models, Communication Processing, Development