Neurosciences
Ben Julian Palanca, MD, PhD, MSc
Associate Professor
- Email: palancab@wustl.edu
Program affiliation
Neurosciences
Research summary
Dr. Palanca has NIH-funded investigations on acute confusion after cardiac surgery and leveraging the anesthetic propofol to modulate sleep to treat depression and cognitive impairment.
Key words
Anesthesia, delirium, sleep, surgery, electroencephalography, imaging, fMRI, consciousness, cognition, encephalopathy, depression, antidepressant
Michael Paley, MD, PhD
Assistant Professor
- Email: paleym@wustl.edu
Program affiliation
Immunology
Computational and Systems Biology
Neurosciences
Research summary
Mechanisms of inflammation in immune-privileged organs
Key words
Thomas Papouin, PhD
Assistant Professor
- Email: thomas.papouin@wustl.edu
Program affiliation
Neurosciences
Research summary
Mechanisms or neuron-glia interactions in health and disease
Key words
Astrocytes, Synapses, Neuromodulation, Behavior, Electrophysiology,
Bhuvic Patel, MD
Assistant Professor
- Email: bhuvic.patel@wustl.edu
Program affiliation
Neurosciences
Cancer Biology
Computational and Systems Biology
Research summary
Our lab employs cutting-edge molecular biology techniques to investigate the genetic, epigenetic, and cellular alterations driving the initiation, progression, and therapeutic resistance of brain tumors.
Key words
brain tumors, systems biology, genetics, neurosurgery, neurooncology
Guangyong Peng, MD, PhD
Professor
- Email: pengg@wustl.edu
Program affiliation
Immunology
Cancer Biology
Neurosciences
Research summary
Understanding the role of immune system in the pathogenesis of cancer and age-related neurological disorders (Alzheimer's disease), and then to develop effective strategies for manipulation of immune cell fate and function for disease prevention and immunotherapy.
Key words
Senescent T cells, Regulatory T cells (Tregs), Dendritic cells (DCs), Tumor microenvironment, Alzheimer's disease, Cell metabolism, Toll-like receptors, Immunotherapy
Susan B. Perlman, PhD
Associate Professor
- Email: perlmansusan@wustl.edu
Program affiliation
Neurosciences
Research summary
Key words
Joel S. Perlmutter, MD
Professor
- Email: perlmutterjoel@wustl.edu
Program affiliation
Neurosciences
Research summary
Pharmacology, physiology and pathophysiology of basal ganglia and movement disorders
Key words
pathogenesis, neuroimaging, physiology, neurobiology, movement disorders, Parkinson disease, dystonia
Benjamin Philip, PhD
Assistant Professor
- Email: bphilip@wustl.edu
Program affiliation
Neurosciences
Research summary
The interaction between hand dominance, brain lateralization, and rehabilitation following unilateral impairment such as stroke, amputation, or nerve injury
Key words
Jennifer E. Phillips-Cremins, PhD
BJC Investigator and James S. McDonnell Professor
- Email: jennifer.cremins@wustl.edu
Program affiliation
Molecular Genetics and Genomics
Neurosciences
Computational and Systems Biology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Research summary
The Cremins lab integrates molecular and computational biology to elucidate how the genome’s structure-function relationship influences synaptic plasticity and neurophysiology during memory encoding and consolidation and how this goes awry in intractable neurological disorders.
Key words
chromatin, neuroepigenetics, 3D genome, synaptic plasticity, Alzheimer's, repeat expansion disorders, chromatin-synapse communication, neural connectome, organoids
Marco Pignatelli, MD
Assistant Professor
- Email: marco.pignatelli@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Research summary
Understanding the synaptic mechanisms by which emotional experiences lead to maladaptive plasticity and the impact of neurotherapeutic drugs on those maladaptive synaptic neuroadaptations
Key words
synaptic plasticity, Optogenetics, cell-type specific pharmacology, patch clamp electrophysiology, rapid-acting antidepressants, motivated behavior, drug addiction and affective disorders