Neurosciences

Program affiliation
Neurosciences
Biomedical Informatics and Data Science

Research summary
Our laboratory develops and uses novel neuroanatomical and neuroimaging computerized brain mapping methods to study the structure, function, connectivity, parcellation, development, and evolution of cerebral cortex in humans and nonhuman primates in health and disease.

Key words
Neuroanatomy Connectomics Neuroimaging Neuroradiology Medical Image Analysis

Program affiliation
Molecular Cell Biology
Neurosciences

Research summary

Key words

Program affiliation
Neurosciences
Developmental Regenerative and Stem Cell Biology
Computational and Systems Biology

Research summary
Understanding the computational principles that underly brain development, using a combination of experimental and theoretical approaches

Key words

Program affiliation
Neurosciences
Biomedical Informatics and Data Science

Research summary
Neuroimaging to better understand the brain in vivo

Key words
aging, neuroimaging, Alzheimer, brain, fMRI, cognitive neuroscience, psychology, cognition, PET

Program affiliation
Neurosciences

Research summary
I use MRI in humans to understand the network organization of the brain in health and disease

Key words

Program affiliation
Neurosciences

Research summary
Integrated advanced imaging approach to studying human brain aging

Key words

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Neurosciences
Computational and Systems Biology
Molecular Cell Biology

Research summary
We work on what induces the inner ear in the first place, how the sensory organs of the ear acquire their exquisite pattern, and whether it will ever be possible to regenerate the sensory hair cells of the inner ear in the deaf and hard-of-hearing.

Key words
inner ear, development, regeneration, sensory neuroscience, balance, deafness, embryo, transcription factors, epigenetics, tunicates, squid

Program affiliation
Neurosciences
Molecular Cell Biology
Immunology

Research summary
We develop innovative magnetic resonance (MR) and position emission tomography (PET) imaging approaches to monitor neuroinflammation, neurodegeneration and repair mechanisms in neurological disorders

Key words
Metabolic imaging, hyperpolarized 13C MRI, positron tomography emission (PET) imaging, neurological disorders, cell tracking, multiple sclerosis, microglia, myelin, immune cells

Program affiliation
Neurosciences
Cancer Biology
Molecular Genetics and Genomics
Developmental Regenerative and Stem Cell Biology

Research summary
Leveraging neurogenetic disorders to study normal brain development, cancer, and autism

Key words
pediatric brain cancer, brain development, neuroimmunology, cancer neuroscience, autism, hiPSC engineering, genetically engineered mice

Program affiliation
Human and Statistical Genetics
Molecular Genetics and Genomics
Computational and Systems Biology
Neurosciences

Research summary
Genetic underpinnings of neurological/neurosurgical disorders

Key words
rare variants, Chiari I malformation, human genetics, neurosurgery, Deep Mutation Scanning, Mutagenesis, Limb-girdle muscular dystrophy