Programs

Program affiliation
Plant and Microbial Biosciences

Research summary
Using genetic approaches to understand the evolutionary and ecological causes and consequences of rarity in endangered plant species

Key words
Conservation genetics, poulation genomics, phylogenomics, botany

Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Human and Statistical Genetics

Research summary
We develop new computational and experimental approaches to understand the roles of DNA methylation and hydroxymethylation in neurodevelopment and cancer

Key words
bioinformatics, cancer, cancer genomics, epigenetics, epigenomics, neurodevelopment, transcriptional regulation

Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology

Research summary
Gene regulation for lymphocyte development and adaptive immune responses

Key words
lymphocyte development, adaptive immunity, transcription factors, cytokines, oncogenesis

Program affiliation
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Neurosciences
Molecular Cell Biology

Research summary
We aim to understand how metabolism influences epigenetics, gene expression and behavior, particularly in the context of substance use disorders and neurodegeneration

Key words
Metabolism, epigenetics, alcohol, addiction, neurodegeneration, Alzheimer’s

Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology

Research summary
Developing novel tools that extend mapping of brain function beyond current limitations

Key words
optical, autism, congenital heart disease, language, development, HD-DOT, ECMO, brain

Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology

Research summary
Medicinal chemistry with a broad goal of drug design and organic synthesis

Key words
Drug Discovery, Medicinal Chemistry, Organic Synthesis, Nuclear Receptors, Computational Chemistry

Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis

Research summary
Defining the cellular and molecular mechanisms that regulate memory B cell heterogeneity and fate.

Key words

Program affiliation
General

Research summary
Mechanical properties of reconstituted tissues; fluctuation spectroscopy of protein interactions

Key words
cytoskeleton, signal transduction, fluorescence correlation spectroscopy, tissue engineering, cell/tissue mechanics

Program affiliation
Neurosciences
Biochemistry Biophysics and Structural Biology

Research summary
Molecular mechanisms of anesthetic action - Proteomics of GABAA receptors

Key words
Anesthetics, photolabeling, mass spectrometry, proteomics

Program affiliation
Molecular Cell Biology
Immunology
Cancer Biology

Research summary
interactions between bone and immune cells in inflammation and cancer

Key words
arthritis, inflammation, cancer, bone metastases, osteoclasts