Programs
Jonathan Kipnis, PhD
BJC Investigator & Alan A. and Edith L. Wolff Distinguished Professor
- Email: kipnis@wustl.edu
Program affiliation
Immunology
Neurosciences
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
We study complex interactions between the immune and nervous systems in health and disease
Key words
Neuroimmunology; neuroscience; immunology; lymphatics; behavior; Alzheimer’s disease; neurodegeneration; glia; microglia; blood-brain barrier (BBB); meninges
Eynav Klechevsky, PhD
Associate Professor
- Email: eklechevsky@wustl.edu
Program affiliation
Immunology
Cancer Biology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
understand the biology of different human dendritic cells and other myeloid cells as a key for manipulating immune responses in various disease conditions
Key words
Human Immunology, Dendritic Cells, Tumor Immunology, immune dysfunctions, Vaccines
Vitaly A. Klyachko, PhD
Professor
- Email: klyachko@wustl.edu
Program affiliation
Neurosciences
Research summary
Synaptic function and plasticity, neural computations, neurodevelopmental diseases
Key words
Alexander Knights, PhD
Assistant Professor
- Email: aknights@wustl.edu
Program affiliation
Immunology
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Research summary
We are fundamentally interested in the complex cellular and molecular interactions that take place during joint homeostasis and disease.
Key words
Osteoarthritis, Immunology, Crosstalk, Fibrosis, Inflammation
Fanwei Kong, PhD
Assistant Professor
- Email: kongf@wustl.edu
Program affiliation
Biomedical Informatics and Data Science
Computational and Systems Biology
Research summary
Key words
Kerry Kornfeld, MD, PhD
Professor
- Email: kornfeld@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
organismal aging; zinc homeostasis and roles of zinc during cell differentiation.
Key words
aging, metals, zinc, development, sperm activation, signal transduction, homeostasis
Dmitri Kotov, PhD
Assistant Professor
- Email: kotov@wustl.edu
Program affiliation
Immunology
Molecular Microbiology and Microbial Pathogenesis
Computational and Systems Biology
Research summary
My lab works on the host immune response to Mycobacterium tuberculosis. We use mouse models that mimic key aspects of human disease to gain a mechanistic understanding of the host response allowing for the identification of novel targets for host-directed therapies.
Key words
Mycobacterium tuberculosis, innate immunology, macrophages, neutrophils, dendritic cells
Paul T. Kotzbauer, MD, PhD
Professor
- Email: kotzbauerp@wustl.edu
Program affiliation
Neurosciences
Molecular Cell Biology
Research summary
Mechanisms of neurodegeneration in Parkinson`s disease and related disorders
Key words
lipid metabolism, mouse models, neurodegeneration, pathogenesis, phospholipase A2, Parkinson disease
Sándor J. Kovács, PhD, MD
Professor
- Email: sjk@wustl.edu
Program affiliation
General
Research summary
Quantitative cardiovascular physiology, mathematical modeling of systems physiology, imaging
Key words
biophysics, cardiology, cardiovascular physiology, echocardiography, imaging, mathematical modeling
John Krais, PhD
Assistant Professor
- Email: krais@wustl.edu
Program affiliation
Cancer Biology
Molecular Genetics and Genomics
Molecular Cell Biology
Research summary
Our laboratory focuses on the fundamental issues of DNA repair and how they relate to cancer initiation, progression, and therapy responses.
Key words
DNA repair, DNA replication, cancer development, targeted therapy, therapy resistance