Programs
Scott Marek, PhD
Assistant Professor
- Email: smarek@wustl.edu
Program affiliation
Neurosciences
Biomedical Informatics and Data Science
Research summary
Key words
Todd P. Margolis, MD, PhD
Alan A and Edith L Wolff Distinguished Professor and Head of the Department of Ophthalmology and Visual Sciences
- Email: margolist@wustl.edu
Program affiliation
General
Research summary
The cellular and molecular mechanisms that regulate the establishment and maintenance of latent neuronal infection with herpes simplex virus (HSV).
Key words
Stephanie Markovina, MD, PhD
Assistant Professor
- Email: smarkovina@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Research summary
Studies novel metrics to serve dual purpose as biomarkers for prognosis and response to radiation therapy, as well as therapeutic targets for human solid tumors such as cervical and anal cancers.
Key words
Garland R. Marshall, PhD
Professor Emeritus
- Email: garland@wustl.edu
Program affiliation
General
Research summary
Molecular recognition is the key to drug design and the bioactive conformation.
Key words
computational biology, molecular modeling, protein structure, ErbB receptors in oncology, GPCR/G-protein, signal transduction
Edward Marti, PhD
Assistant Professor
- Email: emarti@wustl.edu
Program affiliation
Molecular Cell Biology
Research summary
Key words
Dario Maschi, PhD
Assistant Professor
- Email: dario.maschi@wustl.edu
Program affiliation
General
Research summary
My research investigates how circular RNAs, genetic regulators, and microglial responses influence neuronal health in Alzheimer’s and Parkinson’s disease. I combine human genetics and gene expression data with CRISPR-based approaches, RNA sequencing, and advanced imaging in human iPSC-derived neurons and microglia to connect disease-associated molecular changes with cellular mechanisms. My work also integrates deep learning for image analysis and large language model (LLM) agent workflows for biological data integration and candidate prioritization to guide experimental testing.
Key words
Neurodegeneration; Circular RNA; Neuroinflammation; Human iPSC models; Functional genomics; Artificial intelligence
Dimitrious Mathios, MD
Assistant Professor
- Email: mathios@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Genetics and Genomics
Biomedical Informatics and Data Science
Research summary
Development of liquid biopsy approaches for brain tumors
Key words
liquid biopsy, cfDNA, genetics, epigenetics
Melissa Mavers, MD,PhD
Assistant Professor
- Email: mmmavers@wustl.edu
Program affiliation
Immunology
Molecular Cell Biology
Cancer Biology
Research summary
Harnessing immune cells to prevent and treat graft-versus-host disease
Key words
innate lymphocytes, graft-versus-host disease, cell therapies, cancer
Gabriel Mbalaviele, PhD
Professor
- Email: gmbalaviele@wustl.edu
Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology
Research summary
Role of inflammasomes in disease
Key words
Inflammation, Inflammasomes, Skeleton, Cytokines
Audrey McAlinden, PhD
Associate Professor
- Email: mcalindena@wustl.edu
Program affiliation
Developmental Regenerative and Stem Cell Biology
Research summary
Molecular mechanisms regulating skeletal development
Key words
microRNAs; stem cells; skeletal development and regeneration; cartilage; chondrocyte differentiation; pre-mRNA alternative splicing