Programs

Program affiliation
Cancer Biology
Neurosciences

Research summary
The mission of the Thompson Lab is to discover and target molecular drivers of leptomeningeal dissemination of malignant pediatric brain tumors and develop peptide vaccines targeting CMV antigens expressed in brain tumors.

Key words
pediatric brain tumor, medulloblastoma, vaccine, immunotherapy, leptomeningeal dissemination

Program affiliation
Molecular Cell Biology
Developmental Regenerative and Stem Cell Biology

Research summary
Understanding the impact of parental obesity on offspring liver disease and the mechanisms that mediate the development of chronic diseases in adulthood

Key words

Program affiliation
Cancer Biology

Research summary
We develop and evaluate theranostic agents, dual modality diagnostic and therapeutic agents for disease applications. We considers questions of drug development, disease characterization and biological responses with a focus on near term translational relevance.

Key words
cancer, therapy, radiology, radiation oncology, theranostics

Program affiliation
General

Research summary
Psychophysical and computational investigation of human motor control and learning

Key words
mathematical modeling, neurobiology, behavior

Program affiliation
Computational and Systems Biology
Ecology and Evolutionary Biology

Research summary
Theoretical physics of ecology and evolution; quantitative modeling; analysis of sequencing data

Key words
Theoretical biophysics; Evolution; Microbiome; High-diversity ecology

Program affiliation
Plant and Microbial Biosciences
Computational and Systems Biology
Ecology and Evolutionary Biology
Biomedical Informatics and Data Science

Research summary
Understanding the genetic basis of root growth and environmental plasticity using phenomics

Key words
imaging; plant; genetics; computation; phenotyping; roots; plant x environment

Program affiliation
Cancer Biology
Human and Statistical Genetics
Immunology
Molecular Genetics and Genomics

Research summary
Genomics of breast cancer etiology to identify targetable pathways

Key words
Genomics, biomarkers, metabolic imbalance, mammographic density, breast cancer, colorectal cancer, prevention,

Program affiliation
Immunology

Research summary
Receptor-mediated modulation of NK cell responses in vivo

Key words
innate immunity, NK cells, receptors, signal transduction, tolerance

Program affiliation
Molecular Cell Biology
Molecular Genetics and Genomics
Molecular Microbiology and Microbial Pathogenesis
Biochemistry Biophysics and Structural Biology

Research summary
Epigenetic regulation of phenotypes by propagation of prions in yeast

Key words
amyloid, chaperones, epigenetics, neurodegeneration, prion, yeast

Program affiliation
Developmental Regenerative and Stem Cell Biology
Molecular Cell Biology
Computational and Systems Biology

Research summary
Systems-biology approach to study how cells build tissues with precise patterns and shapes in embryo development

Key words