Biochemistry Biophysics and Structural Biology
Paul Schlesinger, MD, PhD
Associate Professor
- Email: pschlesinger@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Research summary
Intracellular ion transport, chloride, protons, mitochondrial channels, phagosome, parasites, bone mineralization
Key words
apoptosis, ion channel, biophysics, bone, physiology, endocytosis, peptides, bacteria, cancer
Clay Semenkovich, MD
Irene E. and Michael M. Karl Professor
- Email: csemenko@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Genetics and Genomics
Research summary
Molecular and cell biology of atherosclerosis and diabetes
Key words
aging, atherosclerosis, diabetes, lipids, obesity
Jieya Shao, PhD
Associate Professor
- Email: shao.j@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Molecular Genetics and Genomics
Biochemistry Biophysics and Structural Biology
Research summary
Molecular mechanisms and therapeutic potential of novel cancer targets
Key words
cancer, genome stability, targeted therapy, proteostasis, autophagy, DNA replication stress, DNA damage response, phosphorylation
Jin-Yu Shao, PhD
Associate Professor and Associate Chairman
- Email: shao@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Research summary
Cellular and molecular engineering
Key words
blood coagulation, cell/tissue mechanics, inflammation, modeling, molecular biomechanics, protein-protein interaction
Vijay Sharma, PhD
Associate Professor
- Email: sharmav@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Neurosciences
Research summary
Design and Development of Small Organics and Metalloprobes for Radiological Molecular Imaging in Biomedical Science
Key words
Molecular Imaging, PET and SPECT Agents, Myocardial Perfusion, Alzheimer`s Disease, Multidrug Resistance
Chen Shen, PhD
Assistant Professor
- Email: shenc@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Computational and Systems Biology
Immunology
Molecular Microbiology and Microbial Pathogenesis
Research summary
Understand the structural mechanisms of host-pathogen interactions and the inflammasome signaling
Key words
structural biology, innate immunity, pattern recognition receptors, immune recognition, inflammasomes
Leonid Shmuylovich, MD,PhD
Assistant Professor
- Email: shmuylol@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Biomedical Informatics and Data Science
Research summary
Develop optical imaging technologies that address clinical problems with a focus on dermatology
Key words
dermatology imaging engineering pigmentation global heath
Kooresh Shoghi, PhD
Assistant Professor
- Email: shoghik@wustl.edu
Program affiliation
Computational and Systems Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Research summary
Multi-disciplinary research spanning biology of disease mechanisms, engineering and imaging sciences & informatics
Key words
Computational medicine, cancer, systems biology and quantitative imaging
Monica Shokeen, PhD
Associate Professor
- Email: shokeenm@wustl.edu
Program affiliation
Cancer Biology
Molecular Cell Biology
Biochemistry Biophysics and Structural Biology
Immunology
Research summary
Development and evaluation of small- and macro-molecular agents for multi-modal molecular imaging of cancer and cardiovascular diseases
Key words
Jonathan Silva, PhD
Associate Professor
- Email: jonsilva@wustl.edu
Program affiliation
Biochemistry Biophysics and Structural Biology
Molecular Cell Biology
Computational and Systems Biology
Biomedical Informatics and Data Science
Research summary
Engineering to help cardiac arrhythmia patients feel better and live longer.
Key words
Bioelectricity, Arrhythmias, Modeling, Molecular Imaging, Electrophysiology, Induced Pluripotent Stem Cells